Since decades it is known that the activity of cells of the immune system is severely
dysregulated in microgravity, however, the underlying molecular aspects have not been …

In space, living organisms are exposed to multiple stress factors including microgravity and
space radiation. For humans, these harmful environmental factors have been known to …

During space travel, astronauts will experience a unique environment that includes
continuous exposure to microgravity and stressful living conditions. Physiological adaptation …

Microgravity is a novel strategy that may serve as a complementary tool to develop future
cancer therapies. In lung cancer, the influence of microgravity on cellular processes and the …

We investigated the dynamics of immediate and initial gene expression response to different
gravitational environments in human Jurkat T lymphocytic cells and compared expression …

No human has returned to the moon since the end of the Apollo program 47 years ago,
however, new missions are planned for an orbital outpost. Space radiation and the potential …

Spaceflight imposes the risk of skeletal muscle atrophy for astronauts. Two main factors of a
spaceflight that results in deleterious effects are microgravity and cosmic rays in outer space …

Objective Weightlessness simulation due to the simulated microgravity has been shown to
considerably affect behavior of tumor cells. It is aim of this study to evaluate characteristics of …

Background Ionizing radiation (IR) can be extremely harmful for human cells since an
improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation …

To understand the molecular mechanism (s) of how spaceflight affects cellular signaling
pathways, quiescent normal human WI-38 fibroblasts were flown on the STS-93 space …