Chronic alcohol consumption and withdrawal leads to anxiety, escalated alcohol drinking
behavior, and alcohol dependence. Alterations in the function of key structures within the …

The brain continues to develop through adolescence when excessive alcohol consumption
is prevalent in humans. We hypothesized that binge drinking doses of ethanol during …

Intermittent alcohol exposure is a common pattern of adolescent alcohol use that can lead to
binge drinking episodes. Alcohol use is known to modulate the endocannabinoid system …

In rodents, chronic intermittent ethanol vapor exposure (CIE) produces alcohol dependence,
alters the structure and activity of pyramidal neurons and decreases the number of …

Many studies have implicated hippocampal dysregulation in the pathophysiology of alcohol
use disorder (AUD). However, over the past twenty years, a growing body of evidence has …

Excessive alcohol consumption in humans induces deficits in decision making and
emotional processing, which indicates a dysfunction of the prefrontal cortex (PFC). The …

Alcohol dependence is characterized by excessive consumption, loss of control over intake,
and the presence of a withdrawal syndrome, including both motivational and physical …

Withdrawal anxiety following chronic ethanol exposure is often associated with relapse in
recovering alcoholics. It is likely that brain regions regulating anxiety-like behaviors adapt …

Background: The central extended amygdala (cEA) which includes the central nucleus of the
amygdala (CeA) and the lateral posterior bed nucleus of the stria terminalis (BNSTLP), has …

The concept of moderate consumption of ethanol (beverage alcohol) has evolved over time
from considering this level of intake to be nonintoxicating and noninjurious, to …