“Dual sensitive supramolecular curcumin nanoparticles” in “advanced yeast particles” mediate macrophage reprogramming, ROS scavenging and inflammation …

X Han, R Luo, S Qi, Y Wang, L Dai, W Nie, M Lin… - Journal of …, 2023 - Springer
Ulcerative colitis (UC) faces some barriers in oral therapy, such as how to safely deliver
drugs to the colon and accumulate in the colon lesions. Hence, we report an advanced yeast …

Yeast microcapsule mediated natural products delivery for treating ulcerative colitis through anti-inflammatory and regulation of macrophage polarization

X Feng, Q Xie, H Xu, T Zhang, X Li, Y Tian… - … Applied Materials & …, 2022 - ACS Publications
The common and frequent disease, ulcerative colitis (UC), causes serious physical and
mental distress to patients. M2 macrophages have proven to play a role in anti-inflammation …

Oral hydrogel nanoemulsion co-delivery system treats inflammatory bowel disease via anti-inflammatory and promoting intestinal mucosa repair

F Lei, F Zeng, X Yu, Y Deng, Z Zhang, M Xu… - Journal of …, 2023 - Springer
Background Due to oral nano-delivery systems for the treatment of inflammatory bowel
disease (IBD) are often failed to accumulated to the colonic site and could not achieve …

Novel Natural Carrier‐Free Self‐Assembled Nanoparticles for Treatment of Ulcerative Colitis by Balancing Immune Microenvironment and Intestinal Barrier

S Gao, H Zheng, S Xu, J Kong, F Gao… - Advanced …, 2023 - Wiley Online Library
Ulcerative colitis (UC) is a chronic inflammatory illness affecting the colon and rectum, with
current treatment methods being unable to meet the clinical needs of ulcerative colitis …

Modulation of macrophages using nanoformulations with curcumin to treat inflammatory diseases: A concise review

H Sun, M Zhan, S Mignani, D Shcharbin, JP Majoral… - Pharmaceutics, 2022 - mdpi.com
Curcumin (Cur), a traditional Chinese medicine extracted from natural plant rhizomes, has
become a candidate drug for the treatment of diseases due to its anti-inflammatory …

Colon-targeted oral nanoparticles based on ROS-scavenging hydroxyethyl starch-curcumin conjugates for efficient inflammatory bowel disease therapy

C Xu, S Chen, C Chen, Y Ming, J Du, J Mu… - International Journal of …, 2022 - Elsevier
Co-delivery of anti-inflammatory drugs and reactive oxygen species (ROS) scavengers by
stimuli-responsive oral nanoparticles is deemed to be a favorable strategy for inflammatory …

Oral administration of turmeric-derived exosome-like nanovesicles with anti-inflammatory and pro-resolving bioactions for murine colitis therapy

C Liu, X Yan, Y Zhang, M Yang, Y Ma, Y Zhang… - Journal of …, 2022 - Springer
Background Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by
diffuse inflammation of the colonic mucosa and a relapsing and remitting course. The current …

β-1, 3-d-Glucan based yeast cell wall system loaded emodin with dual-targeting layers for ulcerative colitis treatment

X Pu, N Ye, M Lin, Q Chen, L Dong, H Xu, R Luo… - Carbohydrate …, 2021 - Elsevier
Abstract Herein, a β-1, 3-d-glucan based microcarrier, yeast cell wall microparticles (YPs),
was used to develop a food-source-based nano-in-micro oral delivery system for ulcerative …

[HTML][HTML] Nano-in-micro alginate/chitosan hydrogel via electrospray technology for orally curcumin delivery to effectively alleviate ulcerative colitis

C Zhang, X Wang, M Xiao, J Ma, Y Qu, L Zou, J Zhang - Materials & Design, 2022 - Elsevier
Although nano-systems can promote the cellular internalization, polymeric nanoparticles
(NPs) are easily to be destroyed or eliminated in the gastrointestinal tract, which leads to …

Macrophage-biomimetic liposomes delivery of carbon dots nanozymes ameliorate ulcerative colitis by modulating inflammation pathways and remodeling the redox …

Y Ma, J Zhao, Z Deng, B Gao, C Xu, X Yan… - Chemical Engineering …, 2023 - Elsevier
As a recurrent chronic inflammatory intestinal disease, ulcerative colitis (UC) has seriously
affected the life quality of patients. Numerous studies have demonstrated excessive reactive …