Repeated pain during a critical period of development can have long-term behavioral and
physiological consequences in both human and animals. We previously showed that rat …

Preterm infants undergoing untreated, repeated painful procedures as part of their early
experience are more likely to behave differently to pain as they mature than infants who …

Repeated pain during brain development can have long-term consequences in both
humans and animals. We previously showed that maternal care provided to pups …

Early preterm neonates in the Neonatal Intensive Care Unit (NICU) are subjected to
repeated painful procedures which could sensitize their responses to pain and potentiate …

Abuse during childhood is the hallmark of postnatal environmental adversity in humans, and
there is evidence for an association between childhood abuse and chronic pain later in life …

Maternal separation is a widely accepted model for studying long-term behavioral changes
produced by events during early life and its association with changes in pain sensitivity …

Deprivation of maternal care has been associated with higher pain sensitivity in offspring. In
the present study, we hypothesized that the maternal licking/grooming behavior was an …

Previous studies found that stressful events during pregnancy can alter the offspring's pain
sensitivity to the phasic nociceptive stimuli. The present data constitute the first …

The aim of this work was to study the effects of prenatal stress on nociceptive responses in
the formalin test in female and male infant (7-day-old) Long-Evans hooded rats. Prenatally …

Background and aims Newborn infants are vulnerable to procedural stress and pain
exposure on the first weeks of life that represents a critical period for the development of …