Previous work has shown that 5-HT 2C receptor agonists and 5-HT 2A receptor antagonists
reduce impulsive action, as well as the locomotor stimulant effect of psychomotor stimulants …

Rationale: Altered serotonergic and dopaminergic function have been widely implicated in
behavioural disorders associated with impulsivity and risk-taking. However, little research …

Abstract Serotonin (5-HT) is well known to affect the motivational properties of stimuli
predictive of rewards as well as the inhibitory control of behavior. Here, central 5-HT …

Rationale The increasing use of genetically modified mice to probe genetic contributions to
normal and abnormal behaviours requires the development of sensitive and selective …

Rationale and objective Impulsive behavior has been suggested to occur due to a
dysfunction of serotonergic 5-HT neurotransmission. After evaluation by a self-reporting …

Maladaptive impulsivity is a core symptom in various psychiatric disorders. However, there is
only limited evidence available on whether different measures of impulsivity represent …

This study investigated the effects of acute serotonin depletion on two measures of impulsive
behavior in healthy men with a family history of alcoholism. Serotonin has been implicated in …

Animal studies of impulsivity have typically used one of three models: a delay of reward
procedure, a differential reinforcement for low rate responding (DRL) procedure, or an …

Deakin and Graeff proposed that forebrain 5-hydroxytryptamine (5-HT) projections are
activated by aversive events and mediate anticipatory coping responses including …

High levels of impulsive behaviours are a clinically significant symptom in a range of
psychiatric disorders, such as attention deficit hyperactivity disorder, bipolar disorder …