Long-chain fatty acids are important metabolites for the generation of energy and the
biosynthesis of lipids. The molecular mechanism of their cellular uptake has remained …

The current state of knowledge concerning the absorption and transport of dietary fat with
emphasis on long‐chain polyunsaturated n− 3 fatty acids in mammals is reviewed. It is …

Long-chain fatty acyl-CoA synthetase (FACS) catalyzes esterification of long-chain fatty
acids (LCFAs) with coenzyme A (CoA), the first step in fatty acid metabolism. FACS has been …

The role of cytosolic liver fatty acid binding protein (L-FABP) in fatty acid uptake and
metabolism was examined using cultured L-cell fibroblasts transfected with the cDNA …

Evidence from a number of laboratories suggests that membrane proteins may meditate the
transport of physiologic fatty acids (FA) across cell membranes. However, studies using lipid …

Publisher Summary This chapter provides a comprehensive overview of the current state of
knowledge of the research with particular emphasis on evolving concepts of fatty acid …

Uptake of [3H] oleate by canine or rat cardiac myocytes is saturable, displays the
countertransport phenomenon, and is inhibited by phloretin and trypsin. Cardiac myocytes …

Exogenous long chain fatty acids (LCFAs) 1 influence a myriad of cellular processes
including intracellular signaling and patterns of gene expression. Some cell types …

J uxtaposed in this issue of the Proceedings are two short reviews on the cellular uptake of
water-insoluble substances, in this case, long-chain fatty acids. These reviews reflect two …

The transport of long-chain fatty acids across cellular membranes most likely occurs to some
extent by passive diffusion and additionally is facilitated by a number of membrane …