Epigenetic changes induced by curcumin and other natural compounds

S Reuter, SC Gupta, B Park, A Goel, BB Aggarwal - Genes & nutrition, 2011 - Springer
Epigenetic regulation, which includes changes in DNA methylation, histone modifications,
and alteration in microRNA (miRNA) expression without any change in the DNA sequence …

Curcumin as a regulator of epigenetic events

MH Teiten, M Dicato, M Diederich - Molecular nutrition & food …, 2013 - Wiley Online Library
Epigenetic alterations correspond to changes in DNA methylation, covalent modifications of
histones, or altered mi RNA expression patterns. These three mechanisms are …

“Curcumin, the king of spices”: epigenetic regulatory mechanisms in the prevention of cancer, neurological, and inflammatory diseases

SSS Boyanapalli, ANT Kong - Current pharmacology reports, 2015 - Springer
Curcumin (diferuloylmethane), a polyphenolic compound, is a component of Curcuma
longa, commonly known as turmeric. It is a well-known anti-inflammatory, anti-oxidative, and …

Curcumin as an alternative epigenetic modulator: mechanism of action and potential effects

F Hassan, MS Rehman, MS Khan, MA Ali… - Frontiers in …, 2019 - frontiersin.org
Curcumin (a polyphenolic compound in turmeric) is famous for its potent anti-inflammatory,
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …

Development of curcumin as an epigenetic agent

S Fu, R Kurzrock - Cancer, 2010 - Wiley Online Library
The clinical benefits of curcumin as a single agent were demonstrated in patients with
advanced pancreatic cancer in a phase 2 study despite pharmacokinetic analysis showing a …

Curcumin from turmeric rhizome: A potential modulator of DNA methylation machinery in breast cancer inhibition

K Fabianowska-Majewska, A Kaufman-Szymczyk… - Nutrients, 2021 - mdpi.com
One of the most systematically studied bioactive nutraceuticals for its benefits in the
management of various diseases is the turmeric-derived compounds: curcumin. Turmeric …

[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Molecular mechanisms of curcumin action: gene expression

S Shishodia - Biofactors, 2013 - Wiley Online Library
Curcumin derived from the tropical plant Curcuma longa has a long history of use as a
dietary agent, food preservative, and in traditional Asian medicine. It has been used for …

Chemopreventive and therapeutic effects of curcumin

A Duvoix, R Blasius, S Delhalle, M Schnekenburger… - Cancer letters, 2005 - Elsevier
Chemoprevention is a promising anti-cancer approach with reduced secondary effects in
comparison to classical chemotherapy. Curcumin, one of the most studied chemopreventive …

Epigenetic targets of bioactive dietary components for cancer prevention and therapy

SM Meeran, A Ahmed, TO Tollefsbol - Clinical epigenetics, 2010 - Springer
The emergent interest in cancer epigenetics stems from the fact that epigenetic modifications
are implicated in virtually every step of tumorigenesis. More interestingly, epigenetic …