Uterine leiomyomas exhibit fewer stem/progenitor cell characteristics when compared with corresponding normal myometrium
HL Chang, TN Senaratne, LH Zhang, PP Szotek… - Reproductive …, 2010 - Springer
Uterine leiomyomas (also known as uterine fibroids) are the most common benign tumors of
female reproductive tract and are the single most common indication for hysterectomies …
female reproductive tract and are the single most common indication for hysterectomies …
Subtype-specific tumor-associated fibroblasts contribute to the pathogenesis of uterine leiomyoma
Recent genomic studies have identified subtypes of uterine leiomyoma (LM) with distinctive
genetic alterations. Here, we report the elucidation of the biological characteristics of the two …
genetic alterations. Here, we report the elucidation of the biological characteristics of the two …
Treatment strategies for uterine leiomyoma: the role of hormonal modulation
JD Cook, CL Walker - Seminars in reproductive medicine, 2004 - thieme-connect.com
Uterine leiomyomas are the most common gynecological tumors and are a significant health
concern for many women. Although the exact etiology of these tumors is unknown …
concern for many women. Although the exact etiology of these tumors is unknown …
Advances in uterine leiomyoma research: the progesterone hypothesis
MS Rein - Environmental health perspectives, 2000 - JSTOR
Uterine leiomyomas are monoclonal tumors. However, the factors involved in their initiation
and growth remain poorly understood. The neoplastic transformation of myometrium to …
and growth remain poorly understood. The neoplastic transformation of myometrium to …
Leiomyoma: genetics, assisted reproduction, pregnancy and therapeutic advances
Purpose Uterine leiomyomas are common, benign, reproductive tract tumors affecting a
majority of reproductive aged women. They are associated with gynecologic morbidity and …
majority of reproductive aged women. They are associated with gynecologic morbidity and …
Progesterone is essential for maintenance and growth of uterine leiomyoma
H Ishikawa, K Ishi, VA Serna, R Kakazu… - …, 2010 - academic.oup.com
Uterine leiomyomata (ULs) represent the most common tumor in women and can cause
abnormal uterine bleeding, large pelvic masses, and recurrent pregnancy loss. Although the …
abnormal uterine bleeding, large pelvic masses, and recurrent pregnancy loss. Although the …
Uterine leiomyomas: mechanisms of tumorigenesis
KD Houston, DS Hunter, LC Hodges… - Toxicologic …, 2001 - journals.sagepub.com
Uterine leiomyomas, also called fi broids, are the most common reproductive tract neoplasm
and the leading indication for hysterectomy in premenopausal women. The discovery and …
and the leading indication for hysterectomy in premenopausal women. The discovery and …
Effects of progesterone on uterine leiomyoma growth and apoptosis
T Maruo, H Matsuo, T Samoto, Y Shimomura… - Steroids, 2000 - Elsevier
Uterine leiomyomas appear during the reproductive years and regress after menopause,
indicating the ovarian steroid-dependent growth potential. Recently we have found that the …
indicating the ovarian steroid-dependent growth potential. Recently we have found that the …
Identification of new therapies for leiomyomas: what in vitro studies can tell us
RA Nowak - Clinical Obstetrics and Gynecology, 2001 - journals.lww.com
Uterine leiomyomas, or fibroids, are the most common pelvic tumors in women, with a
reported incidence of 20–25%. 1–3 Leiomyomas are clinically important because they are a …
reported incidence of 20–25%. 1–3 Leiomyomas are clinically important because they are a …
[HTML][HTML] Progesterone signaling in uterine leiomyoma biology: Implications for potential targeted therapy
W Szucio, P Bernaczyk, D Ponikwicka-Tyszko… - Advances in Medical …, 2024 - Elsevier
Uterine leiomyomas (ULs) are the most common benign smooth muscle cell steroid-
dependent tumors that occur in women of reproductive age. Progesterone (P4) is a major …
dependent tumors that occur in women of reproductive age. Progesterone (P4) is a major …