The mechanism and function of epigenetics in uterine leiomyoma development

Q Yang, A Mas, MP Diamond… - Reproductive …, 2016 - journals.sagepub.com
Uterine leiomyomas, also known as uterine fibroids, are the most common pelvic tumors,
occurring in nearly 70% of all reproductive-aged women and are the leading indication for …

Epigenomic and enhancer dysregulation in uterine leiomyomas

OW Mlodawska, P Saini, JB Parker… - Human …, 2022 - academic.oup.com
BACKGROUND Uterine leiomyomas, also known as uterine fibroids or myomas, are the
most common benign gynecological tumors and are found in women of reproductive and …

Why leiomyomas are called fibroids: the central role of extracellular matrix in symptomatic women

M Malik, J Norian, D McCarthy-Keith… - Seminars in …, 2010 - thieme-connect.com
Uterine leiomyomas are highly prevalent and symptomatic tumors of women in their
reproductive years. The morbidity caused by these tumors is directly related to increasing …

[HTML][HTML] The second National Institutes of Health International Congress on advances in uterine leiomyoma research: conference summary and future …

D Dixon, EC Parrott, JH Segars, K Olden, VW Pinn - Fertility and sterility, 2006 - Elsevier
OBJECTIVE: To summarize the proceedings of the Advances in Uterine Leiomyoma
Research: 2nd NIH International Congress, which was convened on February 24–25, 2005 …

Pregnancy, parturition, and prostaglandins: defining uterine leiomyomas

K Cesen-Cummings, JA Copland, JC Barrett… - Environmental health …, 2000 - JSTOR
Leiomyomas, benign smooth muscle tumors of the uterus, are the most common
gynecologic neoplasm in women. Studies with surgically resected human tissues and …

[HTML][HTML] Stromal fibroblast activation and their potential association with uterine fibroids

LH Zheng, FF Cai, I Ge, E Biskup… - Oncology …, 2014 - spandidos-publications.com
Uterine fibroids are the most common type of benign, gynecologic neoplasm and are the
primary indication for performance of a hysterectomy, accounting for> 200,000 …

Biology of uterine myomas and myometrium in vitro

MS Rein, RA Nowak - Seminars in reproductive endocrinology, 1992 - thieme-connect.com
Uterine leiomyomas are a major public health problem for women of reproductive age. For
many years, uterine leiomyomas have been the most common indication for hysterectomy …

Progesterone: a critical role in the pathogenesis of uterine myomas

MS Rein, RL Barbieri, AJ Friedman - American journal of obstetrics and …, 1995 - Elsevier
Uterine leiomyomas are monoclonal tumors. However, the factors involved in their initiation
and growth remain poorly understood. The neoplastic transformation of myometrium to …

Racial and ethnic differences in the pathogenesis and clinical manifestations of uterine leiomyoma

WH Catherino, HM Eltoukhi… - Seminars in reproductive …, 2013 - thieme-connect.com
Uterine leiomyomas are the most common benign gynecologic condition. The prevalence is
three times more common among women of African ethnicity. Disparity in this disease is …

Uterine fibroids: hiding in plain sight

EA Stewart, RA Nowak - Physiology, 2022 - journals.physiology.org
Uterine fibroids (leiomyomas) are present in> 75% of women and can cause serious
morbidity. They are by far the leading cause of hysterectomy. Fibroids are a complex mixture …