Cell competition: how to eliminate your neighbours

M Amoyel, EA Bach - Development, 2014 - journals.biologists.com
A conventional view of development is that cells cooperate to build an organism. However,
based on studies of Drosophila, it has been known for years that viable cells can be …

[HTML][HTML] Cell competition: A historical perspective

G Morata - Developmental Biology, 2021 - Elsevier
Cell competition is a homeostatic process designed to remove from animal tissues viable
cells that are unfit, abnormal or malignant and that may compromise the general fitness or …

Cell competition: Emerging mechanisms to eliminate neighbors

R Nagata, T Igaki - Development, growth & differentiation, 2018 - Wiley Online Library
Cell competition is a context‐dependent cell elimination through short‐range cell–cell
interaction, in which cells with higher fitness eliminate neighboring less‐fit or oncogenic …

Mechanisms of cell competition: themes and variations

R Levayer, E Moreno - Journal of cell biology, 2013 - rupress.org
Cell competition is the short-range elimination of slow-dividing cells through apoptosis when
confronted with a faster growing population. It is based on the comparison of relative cell …

New frontiers in cell competition

S de Beco, M Ziosi, LA Johnston - Developmental dynamics, 2012 - Wiley Online Library
Cellular communication is at the heart of animal development, and guides the specification
of cell fates, the movement of cells within and between tissues, and the coordinated …

Cell competition

NE Baker - Current Biology, 2011 - cell.com
It is self-evident that cell–cell interactions play important roles in multicellular organisms.
Genetic mosaics and chimeras, containing cells of distinct genotypes, have long provided an …

Cell competition: mechanisms and physiological roles

C Clavería, M Torres - Annual review of cell and developmental …, 2016 - annualreviews.org
Cell-competitive interactions are widespread in nature and determine the outcome of a vast
variety of biological processes. A particular class of competitive interactions takes place …

Cell competition in development: information from flies and vertebrates

E Madan, R Gogna, E Moreno - Current opinion in cell biology, 2018 - Elsevier
Cell competition is a biological mechanism conserved from Drosophila to vertebrates
wherein neighboring cells compare their relative fitness status resulting in the elimination of …

The competitive nature of cells

B Díaz, E Moreno - Experimental cell research, 2005 - Elsevier
The possibility that cells of multicellular organisms may compete with one another has been
postulated several times. It was experimentally confirmed in Drosophila, probably for the first …

Emerging mechanisms of cell competition

NE Baker - Nature Reviews Genetics, 2020 - nature.com
The growth and survival of cells within tissues can be affected by 'cell competition'between
different cell clones. This phenomenon was initially recognized between wild-type cells and …