Targeting IL-33 in autoimmunity and inflammation
TC Theoharides, AI Petra, A Taracanova… - … of Pharmacology and …, 2015 - ASPET
Interleukin-33 (IL-33) belongs to the IL-1 family of cytokines. Whereas IL-1 is processed and
released by live immune cells in response to infection or other triggers, IL-33 is mostly …
released by live immune cells in response to infection or other triggers, IL-33 is mostly …
Dichotomous function of IL-33 in health and disease: from biology to clinical implications
H Braun, IS Afonina, C Mueller, R Beyaert - Biochemical Pharmacology, 2018 - Elsevier
Abstract Interleukin (IL)-33 is a cytokine that is released from epithelial and endothelial cells
at barrier surfaces upon tissue stress or damage to operate as an alarmin. IL-33 has been …
at barrier surfaces upon tissue stress or damage to operate as an alarmin. IL-33 has been …
Disease-associated functions of IL-33: the new kid in the IL-1 family
FY Liew, NI Pitman, IB McInnes - Nature Reviews Immunology, 2010 - nature.com
Abstract Interleukin-33 (IL-33), a newly described member of the IL-1 family, is expressed by
many cell types following pro-inflammatory stimulation and is thought to be released on cell …
many cell types following pro-inflammatory stimulation and is thought to be released on cell …
Interleukin-33 biology with potential insights into human diseases
G Palmer, C Gabay - Nature Reviews Rheumatology, 2011 - nature.com
Abstract Interleukin (IL)-33 is a member of the IL-1 family of cytokines. IL-33 is a nuclear
protein that is also released into the extracellular space, and thus acts as a dual-function …
protein that is also released into the extracellular space, and thus acts as a dual-function …
IL-33 in autoimmunity; possible therapeutic target
CY Yuan - International immunopharmacology, 2022 - Elsevier
Abstract Interleukin (IL)-33 is a member of the IL-1 cytokine family, which serves as both a
cytokine and a nuclear factor. IL-33 is primarily expressed by keratinocytes, epithelial and …
cytokine and a nuclear factor. IL-33 is primarily expressed by keratinocytes, epithelial and …
Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine
C Cayrol, JP Girard - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
Interleukin-33 in health and disease
FY Liew, JP Girard, HR Turnquist - Nature Reviews Immunology, 2016 - nature.com
Abstract Interleukin-33 (IL-33)—a member of the IL-1 family—was originally described as an
inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now …
inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now …
IL-33: a promising therapeutic target for rheumatoid arthritis?
FL Yuan, X Li, WG Lu, CW Li, RS Xu… - Expert opinion on …, 2011 - Taylor & Francis
Cytokine-mediated immunity plays a crucial role in the pathogenesis of various autoimmune
diseases, including rheumatoid arthritis (RA). Recently, the IL-1-family-related cytokine, IL …
diseases, including rheumatoid arthritis (RA). Recently, the IL-1-family-related cytokine, IL …
Role of IL-33 in inflammation and disease
AM Miller - Journal of inflammation, 2011 - Springer
Abstract Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
Dual immune regulatory roles of interleukin-33 in pathological conditions
H Guo, EA Bossila, X Ma, C Zhao, Y Zhao - Cells, 2022 - mdpi.com
Interleukin-33 (IL-33), a member of the IL-1 cytokine family and a multifunctional cytokine,
plays critical roles in maintaining host homeostasis and in pathological conditions, such as …
plays critical roles in maintaining host homeostasis and in pathological conditions, such as …