Silver nanoparticles in the lung: toxic effects and focal accumulation of silver in remote organs

M Wiemann, A Vennemann, F Blaske, M Sperling… - Nanomaterials, 2017 - mdpi.com
The distribution of silver (Ag) into remote organs secondary to the application of Ag
nanoparticles (Ag-NP) to the lung is still incompletely understood and was investigated in …

Persistence of silver nanoparticles in the rat lung: Influence of dose, size, and chemical composition

DS Anderson, RM Silva, D Lee, PC Edwards… - …, 2015 - Taylor & Francis
Increasing silver nanoparticle (AgNP) use in sprays, consumer products, and medical
devices has raised concerns about potential health effects. While previous studies have …

Influence of particle size on persistence and clearance of aerosolized silver nanoparticles in the rat lung

DS Anderson, ES Patchin, RM Silva… - Toxicological …, 2015 - academic.oup.com
The growing use of silver nanoparticles (AgNPs) in consumer products raises concerns
about potential health effects. This study investigated the persistence and clearance of 2 …

Lung distribution, quantification, co-localization and speciation of silver nanoparticles after lung exposure in mice

S Smulders, C Larue, G Sarret, H Castillo-Michel… - Toxicology letters, 2015 - Elsevier
Large knowledge gaps still exist on the toxicological mechanisms of silver (Ag) engineered
nanoparticles (ENPs); a comprehensive understanding of the sources, biodistribution …

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

AR Gliga, S Skoglund, I Odnevall Wallinder… - Particle and fibre …, 2014 - Springer
Abstract Background Silver nanoparticles (AgNPs) are currently one of the most
manufactured nanomaterials. A wide range of toxicity studies have been performed on …

[HTML][HTML] Pulmonary and hepatic effects after low dose exposure to nanosilver: Early and long-lasting histological and ultrastructural alterations in rat

E Roda, MG Bottone, M Biggiogera, G Milanesi… - Toxicology reports, 2019 - Elsevier
Although environmental airborne silver nanoparticles (AgNPs) levels in occupational and
environmental settings are harmful to humans, the precise toxic effects at the portal entry of …

Difference in the toxicity mechanism between ion and nanoparticle forms of silver in the mouse lung and in macrophages

Y Arai, T Miyayama, S Hirano - Toxicology, 2015 - Elsevier
The health effects of silver nanoparticles (AgNPs) have not been well investigated, despite
AgNPs now being widely used in consumer products. We investigated the metabolic …

Biodistribution and pulmonary metabolic effects of silver nanoparticles in mice following acute intratracheal instillations

F Rosário, IF Duarte, RJB Pinto, C Santos… - … Science and Pollution …, 2021 - Springer
The respiratory tract is the route of entry for accidentally inhaled AgNPs, which can reach the
lungs and redistribute to other main organs through systemic circulation. In the present work …

Particle size dependent deposition and pulmonary inflammation after short-term inhalation of silver nanoparticles

HM Braakhuis, I Gosens, P Krystek, JAF Boere… - Particle and fibre …, 2014 - Springer
Background Although silver nanoparticles are currently used in more than 400 consumer
products, it is not clear to what extent they induce adverse effects after inhalation during …

Aerosolized silver nanoparticles in the rat lung and pulmonary responses over time

RM Silva, DS Anderson, J Peake… - Toxicologic …, 2016 - journals.sagepub.com
Silver nanoparticle (Ag NP) production methods are being developed and refined to
produce more uniform Ag NPs through chemical reactions involving silver salt solutions …