Summary β-catenin plays essential roles in cell adhesion and Wnt signaling, while
deregulation of β-catenin is associated with multiple diseases including cancers. Here, we …

β-catenin is both a crucial regulator of cell adhesion and the central effector of the canonical
Wnt signaling pathway. It functions as a protein organizer by interacting with numerous …

The canonical Wnt pathway plays critical roles in embryonic development, stem cell growth,
and tumorigenesis. Stimulation of the Wnt pathway leads to the association of β-catenin with …

The Wnt signaling pathway plays critical roles in embryonic development and
tumorigenesis. Stimulation of the Wnt pathway results in the accumulation of a nuclear β …

Accumulation of the Wnt pathway effector β-catenin is a hallmark of a number of cancers,
including colon cancer. As β-catenin accumulates in the cell, it forms a complex with Tcf …

The F-actin–binding cytoskeletal protein α-catenin interacts with β-catenin–cadherin
complexes and stabilizes cell-cell junctions. The β-catenin–α-catenin complex cannot bind F …

Beta‐catenin functions as a cytoskeletal linker protein in cadherin‐mediated adhesion and
as a signal mediator in wnt‐signal transduction pathways. We use a novel integrative …

β-Catenin plays essential roles in both cell–cell adhesion and Wnt signal transduction, but
what precisely controls β-catenin targeting to cadherin adhesive complexes, or T-cell factor …

Abstract β-catenin is essential for cadherin-based cell adhesion and Wnt/Wingless growth
factor signaling. In these roles, it binds to cadherins, Tcf-family transcription factors, and the …

Abstract β-catenin is a multifunctional protein involved in both cell adhesion and
transcriptional activation. Transcription mediated by the β-catenin/Tcf complex is involved in …