There is increasing evidence that mood disorders may derive from the impact of
environmental pressure on genetically susceptible individuals. Stress-induced hippocampal …

There is increasing evidence that depression derives from the impact of environmental
pressure on genetically susceptible individuals. We analyzed the effects of chronic mild …

Chronic and acute stressors have been linked to changes in hippocampal function and
anxiety-like behaviors. Both produce changes in gene expression, but the extent to which …

Understanding the individual variability that comes with the likelihood of developing stress-
related psychopathologies is of paramount importance when addressing mechanisms of …

Stress responsiveness, including pain sensitivity and stress-induced analgesia (SIA),
depends on genotype and, partially, is mediated by hippocampus. The present study …

Objective: Acute stress provides many beneficial effects whereas chronic stress contributes
to a variety of human health issues including anxiety, depression, gastrointestinal problems …

Stress causes extensive changes in hippocampal genomic expression, leading to changes
in hippocampal structure and function. The dynamic changes in hippocampal gene …

In the present study, we have coupled the chronic mild stress (CMS) protocol with Affymetrix
microarray technology to screen the rat genome for gene changes in the frontal cortex. The …

Since stress plays a role in the onset and physiopathology of psychiatric diseases, animal
models of chronic stress may offer insights into pathways operating in mood disorders. The …

The inbred mouse strains, C57BL/6 and BALB/c have been used widely in preclinical
psychiatric research. The differences in stress susceptibility of available strains has provided …