DNA methylation: past, present and future directions
KD Robertson, P A. Jones - Carcinogenesis, 2000 - academic.oup.com
DNA methylation, or the covalent addition of a methyl group to cytosine within the context of
the CpG dinucleotide, has profound effects on the mammalian genome. These effects …
the CpG dinucleotide, has profound effects on the mammalian genome. These effects …
DNA methylation, methyltransferases, and cancer
KD Robertson - Oncogene, 2001 - nature.com
The field of epigenetics has recently moved to the forefront of studies relating to diverse
processes such as transcriptional regulation, chromatin structure, genome integrity, and …
processes such as transcriptional regulation, chromatin structure, genome integrity, and …
DNA methylation and cancer
RL Momparler, V Bovenzi - Journal of cellular physiology, 2000 - Wiley Online Library
The methylation of DNA is an epigenetic modification that can play an important role in the
control of gene expression in mammalian cells. The enzyme involved in this process is DNA …
control of gene expression in mammalian cells. The enzyme involved in this process is DNA …
Aberrant DNA methylation in cancer: potential clinical interventions
G Strathdee, R Brown - Expert reviews in molecular medicine, 2002 - cambridge.org
DNA methylation, the addition of a methyl group to the carbon-5 position of cytosine
residues, is the only common covalent modification of human DNA and occurs almost …
residues, is the only common covalent modification of human DNA and occurs almost …
DNA methylation and chromatin–unraveling the tangled web
KD Robertson - Oncogene, 2002 - nature.com
Methylation of cytosines within the CpG dinucleotide by DNA methyltransferases is involved
in regulating transcription and chromatin structure, controlling the spread of parasitic …
in regulating transcription and chromatin structure, controlling the spread of parasitic …
DNA methylation and cancer
M Kulis, M Esteller - Advances in genetics, 2010 - Elsevier
DNA methylation is one of the most intensely studied epigenetic modifications in mammals.
In normal cells, it assures the proper regulation of gene expression and stable gene …
In normal cells, it assures the proper regulation of gene expression and stable gene …
[PDF][PDF] Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis.
Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation
and carcinogenesis Page 1 Carcinogenesis vol.18 no.5 pp.869–882, 1997 COMMENTARY …
and carcinogenesis Page 1 Carcinogenesis vol.18 no.5 pp.869–882, 1997 COMMENTARY …
The role of epigenetic transcription repression and DNA methyltransferases in cancer
FI Daniel, K Cherubini, LS Yurgel, MAZ de Figueiredo… - Cancer, 2011 - Wiley Online Library
Epigenetic alterations such as DNA methylation have been implicated in the development
and progression of various cancers. DNA methylation consists of the reversible addition of a …
and progression of various cancers. DNA methylation consists of the reversible addition of a …
Genomic DNA methylation: the mark and its mediators
Methylation of DNA at position five of the cytosine ring occurs at most CpG dinucleotides in
the mammalian genome and is essential for embryonic viability. With several of the key …
the mammalian genome and is essential for embryonic viability. With several of the key …
DNA methylation and cancer
PC Taberlay, PA Jones - Epigenetics and Disease: Pharmaceutical …, 2011 - Springer
DNA methylation acts in concert with other epigenetic mechanisms to regulate normal gene
expression and facilitate chromatin organization within cells. Aberrant DNA methylation …
expression and facilitate chromatin organization within cells. Aberrant DNA methylation …