Low levels of IgM antibodies against phosphorylcholine—a potential risk marker for ischemic stroke in men
BG Sjöberg, J Su, I Dahlbom, H Grönlund, M Wikström… - Atherosclerosis, 2009 - Elsevier
BACKGROUND: Natural antibodies specific for phosphorylcholine (anti-PC) have been
implicated as protective factors in atherosclerosis. We herein determined the relationship …
implicated as protective factors in atherosclerosis. We herein determined the relationship …
Passive immunization with monoclonal IgM antibodies against phosphorylcholine reduces accelerated vein graft atherosclerosis in apolipoprotein E-null mice
JR Faria-Neto, KY Chyu, X Li, PC Dimayuga, C Ferreira… - Atherosclerosis, 2006 - Elsevier
Phosphorylcholine (PC) headgroup is one of the neoantigens exposed by LDL oxidation
that can elicit an immune response. Active immunization with Streptococcus pneumoniae …
that can elicit an immune response. Active immunization with Streptococcus pneumoniae …
[HTML][HTML] Phosphorylcholine monoclonal antibody therapy decreases intraplaque angiogenesis and intraplaque hemorrhage in murine vein grafts
F Baganha, TJ Sluiter, RCM de Jong… - International Journal of …, 2022 - mdpi.com
Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in
atherosclerosis, due to its atherogenic and proinflammatory effects. PC can be cleared by …
atherosclerosis, due to its atherogenic and proinflammatory effects. PC can be cleared by …
[HTML][HTML] Antibodies against phosphorylcholine among 60-year-olds: Clinical role and simulated interactions
Aims Antibodies against phosphorylcholine (anti-PC) are implicated as protection markers in
atherosclerosis, cardiovascular disease (CVD), and other chronic inflammatory conditions …
atherosclerosis, cardiovascular disease (CVD), and other chronic inflammatory conditions …
[HTML][HTML] Atheroprotective natural anti-phosphorylcholine antibodies of IgM subclass are decreased in Swedish controls as compared to non-westernized individuals …
J Frostegård, WJ Tao, A Georgiades, L Råstam… - Nutrition & …, 2007 - Springer
Objective To determine the importance of IgM antibodies against phosphorylcholine (aPC),
a novel protective factor for cardiovascular disease (CVD), in a population with a non …
a novel protective factor for cardiovascular disease (CVD), in a population with a non …
Low levels of antibodies against phosphorylcholine predict development of stroke in a population-based study from northern Sweden
R Fiskesund, B Stegmayr, G Hallmans, M Vikström… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—Natural immunoglobulin M antibodies specific for
phosphorylcholine (anti-PC) have been implicated in atherosclerosis. We have shown …
phosphorylcholine (anti-PC) have been implicated in atherosclerosis. We have shown …
Natural antibodies against phosphorylcholine as potential protective factors in SLE
J Su, X Hua, H Concha, E Svenungsson… - …, 2008 - academic.oup.com
Objective. We have recently reported that natural antibodies against phosphorylcholine (anti-
PC) have atheroprotective properties. Here we compare anti-PC with other autoantibodies in …
PC) have atheroprotective properties. Here we compare anti-PC with other autoantibodies in …
IgM antibodies against phosphorylcholine promote polarization of T regulatory cells from patients with atherosclerotic plaques, systemic lupus erythematosus and …
Background and aims IgM antibodies against phosphorylcholine (anti-PC) are negatively
associated with atherosclerosis, cardiovascular disease (CVD) and systemic lupus …
associated with atherosclerosis, cardiovascular disease (CVD) and systemic lupus …
Autoantibodies to phosphorylcholine and cardiovascular outcomes in patients with acute coronary syndromes in the ATLAS ACS-TIMI 46 trial
BJ Geller, JL Mega, DA Morrow, J Guo… - Journal of thrombosis …, 2014 - Springer
Atherogenesis is a complex inflammatory process stemming from the accumulation and
oxidation of low density lipoproteins (LDL). IgM autoantibodies against phosphorylcholine …
oxidation of low density lipoproteins (LDL). IgM autoantibodies against phosphorylcholine …
Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension
J Su, A Georgiades, R Wu, T Thulin, U de Faire… - Atherosclerosis, 2006 - Elsevier
OBJECTIVE: To determine the importance of antibodies against phosphorylcholine (PC) and
oxidized low density lipoprotein (OxLDL) for development of atherosclerosis. METHODS …
oxidized low density lipoprotein (OxLDL) for development of atherosclerosis. METHODS …