Concept: Fatigue is a major concern for patients with multiple sclerosis (MS). A clear
definition of MS-related fatigue is a prerequisite for appropriate instruments for fatigue …

Fatigue is a very common symptom among people with multiple sclerosis (MS), but its
management in clinical practice is limited by the lack of clear evidence about the pathogenic …

Background Fatigue is a common symptom in patients with multiple sclerosis. Several
studies suggest that outdoor temperature can impact fatigue severity, but a systematic study …

Background: As a symptom of multiple sclerosis (MS), fatigue is difficult to manage because
of its unknown etiology, the lack of efficacy of the drugs tested to date and the absence of …

Background: Fatigue is common and disabling in multiple sclerosis, yet its physiologic
substrates remain poorly defined. The aim of this study was to determine the relationship …

Fatigue is a complaint often made by multiple sclerosis patients. Description of the symptom
varies from patient to patient. This paper proposes a descriptive and quantitative scale for …

Background and purpose: Fatigue is a common, but still one of the least understood
symptoms in multiple sclerosis (MS). We aimed to investigate whether fatigue was …

Background Reliably monitoring changes in fatigue is an ongoing concern. Objective
Evaluate reliable change using the Modified Fatigue Impact Scale 5-item version (MFIS-5) in …

Although fatigue is common among multiple sclerosis (MS) patients, evaluation of this
symptom is difficult due to the subjectivity and variability of the complaint. We proposed the …

Fatigue in multiple sclerosis is a key symptom associated with work-related problems and
poor quality of life outcomes. The five-item Modified Fatigue Impact Scale is a brief self …