Mechanism of anti-angiogenic property of gold nanoparticles: role of nanoparticle size and surface charge

RR Arvizo, S Rana, OR Miranda, R Bhattacharya… - … , biology and medicine, 2011 - Elsevier
Discovering therapeutic inorganic nanoparticles (NPs) is evolving as an important area of
research in the emerging field of nanomedicine. Recently, we reported the anti-angiogenic …

Gold nanoparticles and angiogenesis: molecular mechanisms and biomedical applications

RS Darweesh, NM Ayoub, S Nazzal - International journal of …, 2019 - Taylor & Francis
Angiogenesis is the formation of new blood vessels from pre-existing vessels. It is a highly
regulated process as determined by the interplay between pro-angiogenic and anti …

Biological properties of “naked” metal nanoparticles

R Bhattacharya, P Mukherjee - Advanced drug delivery reviews, 2008 - Elsevier
Over the past few decades, inorganic nanoparticles, which exhibit significantly distinct
physical, chemical and biological properties from their bulk counterpart's, have elicited much …

Antiangiogenic properties of nanoparticles: a systematic review

BA Saeed, V Lim, NA Yusof, KZ Khor… - International journal …, 2019 - Taylor & Francis
Nanoparticles appear to be one of the most promising agents that offer efficacy in
angiogenesis-related disease therapy. The objective of this research is to systematically …

Gold nanoparticles induce nanostructural reorganization of VEGFR2 to repress angiogenesis

Y Pan, H Ding, L Qin, X Zhao, J Cai… - Journal of biomedical …, 2013 - ingentaconnect.com
The inhibition of the binding between VEGFs and their receptors reduces angiogenesis and
retards tumor growth. Owing to the large amount of antibodies required, the antibody-based …

Effects of aggregation and the surface properties of gold nanoparticles on cytotoxicity and cell growth

W Cui, J Li, Y Zhang, H Rong, W Lu, L Jiang - … , Biology and Medicine, 2012 - Elsevier
The effect of gold nanoparticles (Au NPs) on cells remains open for investigation. Here we
show that small Au NPs can be endocytosed by cells and form aggregates inside the cell …

Gold and silver nanoparticles conjugated with heparin derivative possess anti-angiogenesis properties

MM Kemp, A Kumar, S Mousa, E Dyskin… - …, 2009 - iopscience.iop.org
Silver and gold nanoparticles display unique physical and biological properties that have
been extensively studied for biological and medical applications. Typically, gold and silver …

Antiangiogenic properties of silver nanoparticles

S Gurunathan, KJ Lee, K Kalishwaralal… - Biomaterials, 2009 - Elsevier
Angiogenesis is an important phenomenon involved in normal growth and wound healing
processes. An imbalance of the growth factors involved in this process, however, causes the …

Pharmacological role of functionalized gold nanoparticles in disease applications

WC Ko, SJ Wang, CY Hsiao, CT Hung, YJ Hsu… - Molecules, 2022 - mdpi.com
Gold has always been regarded as a symbol of nobility, and its shiny golden appearance
has always attracted the attention of many people. Gold has good ductility, molecular …

Gold nanoparticles inhibit the proliferation of multiple myeloma cells

R Bhattacharya, CR Patra, R Verma… - Advanced …, 2007 - Wiley Online Library
Multiple myeloma (MM) is a monoclonal plasma-cell malignancy that, despite intensive
investigation, remains universally fatal.[1] Clinically, it is characterized by high levels of …