DNA methylation plays a pivotal role during development in mammals and is central to
transcriptional silencing. The DNA methyltransferases (DNMTs) are responsible for the …

DNA methylation is an essential epigenetic mark in mammals. The proper distribution of this
mark depends on accurate deposition and maintenance mechanisms, and underpins its …

DNA methylation at the 5-position of cytosine (5mC) plays vital roles in mammalian
development. DNA methylation is catalyzed by DNA methyltransferases (DNMTs), and the …

DNA methylation plays a central role in the epigenetic regulation of gene expression during
development and disease. Remarkably, the complex and changing patterns of genomic …

DNA methyltransferases (DNMTs) establish and maintain DNA methylation patterns at
specific regions of the genome, thereby contributing to gene regulation. It is becoming …

DNA methyltransferases (DNMTs) play an essential role in DNA methylation and
transcriptional regulation in the genome. DNMTs, along with other poorly studied elements …

The DNA methyltransferases (Dnmts) are responsible for the generation of genomic
methylation patterns, which lead to transcriptional silencing. Recent studies have identified …

The DNA cytosine methyltransferase 1 (DNMT1) is a ubiquitous nuclear enzyme that
catalyzes the well-established reaction of placing methyl groups on the unmethylated …

The DNA methyltransferase (DNMT) family comprises a conserved set of DNA-modifying
enzymes that have a central role in epigenetic gene regulation. Recent studies have shown …

Mammalian DNA methyltransferases (DNMTs) establish and maintain genomic DNA
methylation patterns that are required for proper epigenetic regulation of gene expression …