Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans

H Ariyasu, K Takaya, T Tagami, Y Ogawa… - The Journal of …, 2001 - academic.oup.com
Ghrelin, an endogenous ligand for the GH secretagogue receptor, was isolated from rat
stomach and is involved in a novel system for regulating GH release. Although previous …

Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion

T Shiiya, M Nakazato, M Mizuta, Y Date… - The Journal of …, 2002 - academic.oup.com
Ghrelin, a novel GH-releasing peptide isolated from human and rat stomach, stimulates food
intake and GH secretion. We determined plasma ghrelin concentrations in patients with …

Circulating ghrelin levels are decreased in human obesity

M Tschop, C Weyer, PA Tataranni, V Devanarayan… - Diabetes, 2001 - Am Diabetes Assoc
Ghrelin is a novel endogenous natural ligand for the growth hormone (GH) secretagogue
receptor that has recently been isolated from the rat stomach. Ghrelin administration …

Loss of meal-induced decrease in plasma ghrelin levels in patients with anorexia nervosa

J Nedvídková, I Krykorková, V Barták… - The Journal of …, 2003 - academic.oup.com
Studies have shown that ghrelin plays a major role in energy homeostasis and modulation
of feeding behavior. However, little is known about the influence of food consumption on …

Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration

K Toshinai, MS Mondal, M Nakazato, Y Date… - Biochemical and …, 2001 - Elsevier
Ghrelin is a novel gut–brain peptide that binds to the growth hormone secretagogue
receptor (GHS-R), thereby functioning in the regulation of growth hormone (GH) release and …

Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach

SG Moesgaard, B Ahrén, RD Carr, DX Gram… - Regulatory peptides, 2004 - Elsevier
Ghrelin is a peptide identified as an endogenous ligand for the growth hormone
secretagogue receptor. Studies have shown that ghrelin stimulates growth hormone …

Differential responses of circulating ghrelin to high-fat or high-carbohydrate meal in healthy women

P Monteleone, R Bencivenga… - The Journal of …, 2003 - academic.oup.com
The effects of specific nutritional factors on ghrelin secretion have not been investigated in
humans. Therefore, we assessed ghrelin responses to a high-carbohydrate meal (1217 kcal …

Postprandial plasma ghrelin is suppressed proportional to meal calorie content in normal-weight but not obese subjects

CW Le Roux, M Patterson, RP Vincent… - The Journal of …, 2005 - academic.oup.com
Circulating levels of the gastric hormone ghrelin rise before and decrease after a meal. In
normal-weight subjects, postprandial suppression of ghrelin is proportional to calories …

Characterization of ghrelin-like immunoreactivity in human plasma

M Patterson, KG Murphy, CW le Roux… - The Journal of …, 2005 - academic.oup.com
Ghrelin is a gastric peptide hormone that has an important role in appetite control and GH
release. Circulating ghrelin levels are inversely correlated with body mass index and …

Expression of ghrelin and its receptor in human tissues

B Ueberberg, N Unger, W Saeger… - Hormone and …, 2009 - thieme-connect.com
Ghrelin is a peptide thought to be involved in the regulation of appetite. Furthermore,
significant effects on the release of growth hormone (GH) and ACTH were demonstrated …