Speech movement measures as markers of bulbar disease in amyotrophic lateral sclerosis

S Shellikeri, JR Green, M Kulkarni, P Rong… - Journal of Speech …, 2016 - ASHA
Purpose The goal of this study was to identify the effects of amyotrophic lateral sclerosis
(ALS) on tongue and jaw control, both cross-sectionally and longitudinally. The data were …

Lower motor neuron involvement in ALS assessed by motor unit number index (MUNIX): Long-term changes and reproducibility

D Fathi, B Mohammadi, R Dengler, S Böselt… - Clinical …, 2016 - Elsevier
Objective Motor unit number estimation (MUNE) techniques such as motor unit number
index (MUNIX) have been used to quantify lower motor neuron loss and disease …

Quantitative voice analysis in the assessment of bulbar involvement in amyotrophic lateral sclerosis

D Robert, J Pouget, A Giovanni, JP Azulay… - Acta oto …, 1999 - Taylor & Francis
Bulbar and pseudobulbar symptoms are diagnostic criteria of amyotrophic lateral sclerosis
(ALS). One of the earliest symptoms of bulbar involvement is voice deterioration. Until now …

Diagnostic utility of gold coast criteria in amyotrophic lateral sclerosis

A Hannaford, N Pavey, M van den Bos… - Annals of …, 2021 - Wiley Online Library
Objective The diagnosis of amyotrophic lateral sclerosis (ALS) remains problematic, with
current diagnostic criteria (revised El Escorial [rEEC] and Awaji) being complex and prone to …

Cross-sectional evaluation of clinical neuro-ophthalmic abnormalities in an amyotrophic lateral sclerosis population

HE Moss, L McCluskey, L Elman, K Hoskins… - Journal of the …, 2012 - Elsevier
OBJECTIVE: Ocular motility abnormalities may be a marker of neuro-degeneration beyond
motor neurons in amyotrophic lateral sclerosis (ALS). We formally compared clinical neuro …

Multiple orofacial indices in amyotrophic lateral sclerosis

R DePaul, BR Brooks - Journal of Speech, Language, and Hearing …, 1993 - ASHA
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by significant speech and swallowing problems resulting from upper and …

Longitudinal analysis of progression of dysphagia in amyotrophic lateral sclerosis

R Higo, N Tayama, T Nito - Auris Nasus Larynx, 2004 - Elsevier
Objective: To investigate the progression of dysphagia in amyotrophic lateral sclerosis (ALS)
using videofluoroscopy (VF), according to two different scales: the duration following bulbar …

An overview of screening instruments for cognition and behavior in patients with ALS: selecting the appropriate tool for clinical practice

IK Gosselt, TCW Nijboer, MA Van Es - … Lateral Sclerosis and …, 2020 - Taylor & Francis
Objective: Patients with amyotrophic lateral sclerosis (ALS) not only show motor deficits, but
may also have cognitive and/or behavioral impairments. Recognizing these impairments is …

The neuropathological signature of bulbar-onset ALS: a systematic review

S Shellikeri, V Karthikeyan, R Martino, SE Black… - Neuroscience & …, 2017 - Elsevier
ALS is a multisystem disorder affecting motor and cognitive functions. Bulbar-onset ALS
(bALS) may be preferentially associated with cognitive and language impairments …

Assessment of the factorial validity and reliability of the ALSFRS-R: a revision of its measurement model

LA Bakker, CD Schröder, MA van Es, P Westers… - Journal of …, 2017 - Springer
The amyotrophic lateral sclerosis functional rating scale-revised (ALSFRS-R) is a widely
used primary outcome measure in amyotrophic lateral sclerosis (ALS) clinical practice and …