The pathology of chronic obstructive pulmonary disease

JC Hogg, W Timens - Annual Review of Pathology: Mechanisms …, 2009 - annualreviews.org
The pathogenesis of chronic obstructive pulmonary disease (COPD) is based on the innate
and adaptive inflammatory immune response to the inhalation of toxic particles and gases …

Pathogenesis of chronic obstructive pulmonary disease

W MacNee - Clinics in chest medicine, 2007 - Elsevier
The pathogenesis of chronic obstructive pulmonary disease (COPD) encompasses a
number of injurious processes, including an abnormal inflammatory response in the lungs to …

New concepts in the pathobiology of chronic obstructive pulmonary disease

V Kim, TJ Rogers, GJ Criner - Proceedings of the American …, 2008 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is characterized by an abnormal persistent
inflammatory response to cigarette smoke. This noxious insult leads to emphysema and …

[HTML][HTML] Pathogenesis of chronic obstructive pulmonary disease

RM Tuder, I Petrache - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
The current epidemic of chronic obstructive pulmonary disease (COPD) has produced a
worldwide health care burden, approaching that imposed by transmittable infectious …

New concepts in chronic obstructive pulmonary disease

PJ Barnes - Annual review of medicine, 2003 - annualreviews.org
Chronic obstructive pulmonary disease (COPD) is a leading cause of death and disability
but has only recently been explored from a cellular and molecular perspective. In COPD …

Pathogenesis of inflammation and repair in advanced COPD

WD Cornwell, V Kim, C Song… - Seminars in respiratory …, 2010 - thieme-connect.com
Chronic obstructive pulmonary disease is characterized by an abnormal persistent
inflammatory response to noxious environmental stimuli, most commonly cigarette smoke …

Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease

T Yoshida, RM Tuder - Physiological reviews, 2007 - journals.physiology.org
Chronic obstructive pulmonary diseases (COPD), comprised of pulmonary emphysema,
chronic bronchitis, and structural and inflammatory changes of small airways, is a leading …

Remodeling in response to infection and injury: airway inflammation and hypersecretion of mucus in smoking subjects with chronic obstructive pulmonary disease

P Maestrelli, M Saetta, CE MAPP… - American journal of …, 2001 - atsjournals.org
Airway epithelium represents the first line of defense against toxic inhalants. In some
subjects, cigarette smoking causes airway inflammation, hypersecretion of mucus, and …

Chronic obstructive pulmonary disease: a chronic systemic inflammatory disease

SF Van Eeden, DD Sin - Respiration, 2008 - karger.com
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation in
both the airways causing airway obstruction and the lung tissues causing emphysema. The …

Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction

KF Chung, IM Adcock - European Respiratory Journal, 2008 - Eur Respiratory Soc
Chronic obstructive pulmonary disease is a leading global cause of morbidity and mortality
that is characterised by inexorable deterioration of small airways obstruction with …