Background Despite concerns about the burden of the bacterial and fungal infection
syndromes related to injection drug use (IDU), robust estimates of the public health burden …

PURPOSE: The purpose of this study was to study the outcome of patients with injection
drug use–associated infective endocarditis (IDU-IE) admitted to an intensive care unit (ICU) …

The epidemiology of infective endocarditis (IE) continues to evolve in areas affected by the
opioid epidemic. Understanding the demographics of the disease allows us to better tailor …

Background: The clinical profile and outcome of nosocomial and non-nosocomial health
care–associated native valve endocarditis are not well defined. Objective: To compare the …

Background Infective endocarditis (IE) requiring surgical intervention in patients who actively
inject drugs poses treatment challenges. Decisions regarding the need for operation are …

Background The objective of this paper was to examine temporal changes of infective
endocarditis (IE) incidence and epidemiology in North America. Methods A systematic …

Background We examined discharges for infective endocarditis (IE) at an academic teaching
hospital for over 10 years to evaluate if an increase in hospitalizations for IE and increase in …

Background Injection drug use has far-reaching social, economic, and health
consequences. Serious bacterial infections, including skin/soft tissue infections …

The proportional incidence of intravenous drug use (IVDU)-associated infective endocarditis
(IE) cases requiring surgery has increased significantly, mirroring the national opioid crisis …

Background Infective endocarditis (IE) is associated with significant mortality and morbidity
despite recent advances in management. Injecting drug use (IDU) remains an important risk …