Beyond yellow curry: assessing commercial curcumin absorption technologies

BJ Douglass, DL Clouatre - Journal of the American College of …, 2015 - Taylor & Francis
BACKGROUND: Few natural products have demonstrated the range of protective and
therapeutic promise as have turmeric and its principal bioactive components: curcumin …

Increasing post‐digestive solubility of curcumin is the most successful strategy to improve its oral bioavailability: A randomized cross‐over trial in healthy adults and In …

S Flory, N Sus, K Haas, S Jehle… - Molecular nutrition & …, 2021 - Wiley Online Library
Scope Different mechanistic approaches to improve the low oral bioavailability of curcumin
have been developed, but not yet directly compared in humans. Methods and Results In a …

A comparative pharmacokinetic assessment of a novel highly bioavailable curcumin formulation with 95% curcumin: A randomized, double-blind, crossover study

SJ Stohs, J Ji, LR Bucci, HG Preuss - Journal of the American …, 2018 - Taylor & Francis
Objective: Curcumin exhibits many beneficial health-promoting characteristics. However, its
poor oral absorption precludes its general use. This study assessed the bioavailability of a …

Bioavailable curcumin formulations: A review of pharmacokinetic studies in healthy volunteers

R Jamwal - Journal of integrative medicine, 2018 - Elsevier
Curcumin is a widely studied natural compound which has shown tremendous in vitro
therapeutic potential. Despite that, the clinical efficacy of the native curcumin is weak due to …

[HTML][HTML] Comparative absorption of curcumin formulations

R Jäger, RP Lowery, AV Calvanese, JM Joy, M Purpura… - Nutrition journal, 2014 - Springer
Background The potential health benefits of curcumin are limited by its poor solubility, low
absorption from the gut, rapid metabolism and rapid systemic elimination. The purpose of …

A unifying perspective in blunting the limited oral bioavailability of curcumin: A succinct look

P Balakumar, T Alqahtani, A Alqahtani… - Current drug …, 2022 - ingentaconnect.com
Background: Curcumin is a polyphenolic compound derived from rhizomes of Curcuma
longa, the golden spice. Curcumin has drawn much attention in recent years of biomedical …

[HTML][HTML] Pharmacokinetics of a single dose of turmeric curcuminoids depends on formulation: results of a human crossover study

P Fança-Berthon, M Tenon, S Le Bouter-Banon… - The Journal of …, 2021 - Elsevier
Background Curcuminoids from turmeric rhizome have significant health benefits but low
bioavailability. Objectives To assess the pharmacokinetics of a novel natural turmeric dried …

[HTML][HTML] Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects

M Purpura, RP Lowery, JM Wilson, H Mannan… - European journal of …, 2018 - Springer
Purpose The optimal health benefits of curcumin are limited by its low solubility in water and
corresponding poor intestinal absorption. Cyclodextrins (CD) can form inclusion complexes …

The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes

C Schiborr, A Kocher, D Behnam… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Curcumin revealed various health‐beneficial properties in numerous studies.
However its bioavailability is low due to its limited intestinal uptake and rapid metabolism …

[HTML][HTML] Highly bioavailable forms of curcumin and promising avenues for curcumin-based research and application: a review

SJ Stohs, O Chen, SD Ray, J Ji, LR Bucci, HG Preuss - Molecules, 2020 - mdpi.com
Curcumin exerts a wide range of beneficial physiological and pharmacological activities,
including antioxidant, anti-amyloid, anti-inflammatory, anti-microbial, anti-neoplastic …