Standardization of ischemia-modified albumin testing: adjustment for serum albumin

G Lippi, M Montagnana, GL Salvagno, GC Guidi - 2007 - degruyter.com
The diagnostic approach to acute myocardial infarction (AMI) is still one of the most
challenging and controversial medical issues. Although the measurement of cardiospecific …

Clinical and analytical review of ischemia‐modified albumin measured by the albumin cobalt binding test

FS Apple - Advances in Clinical Chemistry, 2005 - Elsevier
Publisher Summary The chapter presents a general overview of the clinical and analytical
issues pertaining to the albumin–cobalt binding (ACB) test that measures ischemia-modified …

Ischemia-modified albumin improves the usefulness of standard cardiac biomarkers for the diagnosis of myocardial ischemia in the emergency department setting

S Anwaruddin, JL Januzzi Jr, AL Baggish… - American journal of …, 2005 - academic.oup.com
We studied the role of ischemia-modified albumin (IMA) with standard biomarkers
(myoglobin, creatine kinase-MB [CK-MB], troponin I [TnI]) in assessment of 200 patients with …

Ischemia-modified albumin concentrations should be interpreted with caution in patients with low serum albumin concentrations

DC Gaze, L Crompton, P Collinson - Medical Principles and Practice, 2006 - karger.com
Objective: Ischemia-modified albumin (IMA®) is a novel marker for assessing cardiac
ischaemia. We assessed the relationship between total albumin concentrations and IMA in …

Application of albumin-adjusted ischemia modified albumin index as an early screening marker for acute coronary syndrome

YW Lee, HJ Kim, YH Cho, HB Shin, TY Choi, YK Lee - Clinica Chimica Acta, 2007 - Elsevier
BACKGROUND: Existing cardiac markers are not sensitive for reversible myocardial
ischemia. Ischemia modified albumin (IMA) has recently been shown to be an early and …

Ischemia modified albumin changes–review and clinical implications

E Sbarouni, P Georgiadou, V Voudris - Clinical Chemistry and …, 2011 - degruyter.com
Ischemia modified albumin (IMA), as measured using the albumin cobalt binding test, is
currently the most promising biomarker for early detection of ischemia before the onset of …

Ischemia modified albumin: a novel biomarker for the detection of cardiac ischemia

DC Gaze - Drug metabolism and pharmacokinetics, 2009 - Elsevier
The diagnosis of cardiac ischemia remains a challenge in contemporary emergency
medicine. A blood-borne biomarker is an attractive alternative to cardiac imaging or stress …

Ischemia-modified albumin during skeletal muscle ischemia

E Zapico-Muñiz, M Santaló-Bel… - Clinical …, 2004 - academic.oup.com
Ischemia-modified albumin (IMA) has been proposed as a biological marker of myocardial
ischemia (1, 2). Exposure to ischemic myocardium modifies circulating albumin at its NH2 …

Ischemia-modified albumin measurements in symptom-limited exercise myocardial perfusion scintigraphy reflect serum albumin concentrations but not myocardial …

PM van der Zee, HJ Verberne, JP van Straalen… - Clinical …, 2005 - academic.oup.com
The albumin cobalt-binding test (Ischemia Technologies), which measures the concentration
of ischemia-modified albumin (IMA), has been cleared by the US Food and Drug …

Albumin cobalt binding assay to rule out acute coronary syndrome

JM Abadie, CL Blassingame… - Annals of Clinical & …, 2005 - Assoc Clin Scientists
The purpose of this study was to validate the Albumin Cobalt Binding (ACB®) assay at the
Seattle Veterans Affairs (VA) Hospital to determine if it would provide an earlier rule-out of …