Diagnosis and therapeutic approaches to transthyretin amyloidosis
Y Ando, M Ueda - Current medicinal chemistry, 2012 - ingentaconnect.com
Hereditary amyloidogenic transthyretin (TTR)(ATTR) amyloidosis is an autosomal dominant
form of fatal hereditary amyloidosis. Owing to progress in biochemical and molecular genetic …
form of fatal hereditary amyloidosis. Owing to progress in biochemical and molecular genetic …
Hereditary transthyretin amyloidosis overview
F Manganelli, GM Fabrizi, M Luigetti, P Mandich… - Neurological …, 2020 - Springer
Hereditary amyloidogenic transthyretin (ATTRv) amyloidosis is a rare autosomal dominantly
inherited disorder caused by mutations in the transthyretin (TTR) gene. The pathogenetic …
inherited disorder caused by mutations in the transthyretin (TTR) gene. The pathogenetic …
Recent progress in the understanding and treatment of transthyretin amyloidosis
Y Sekijima - Journal of clinical pharmacy and therapeutics, 2014 - Wiley Online Library
What is known and objective Transthyretin (TTR) is a representative amyloidogenic protein
in humans. Rate‐limiting tetramer dissociation and rapid monomer misfolding and …
in humans. Rate‐limiting tetramer dissociation and rapid monomer misfolding and …
Transthyretin (ATTR) amyloidosis: clinical spectrum, molecular pathogenesis and disease-modifying treatments
Y Sekijima - Journal of Neurology, Neurosurgery & Psychiatry, 2015 - jnnp.bmj.com
Transthyretin (ATTR) amyloidosis is a life-threatening, gain-of-toxic-function disease
characterised by extracellular deposition of amyloid fibrils composed of transthyretin (TTR) …
characterised by extracellular deposition of amyloid fibrils composed of transthyretin (TTR) …
Transthyretin: Its function and amyloid formation
M Ueda - Neurochemistry International, 2022 - Elsevier
Transthyretin (TTR), which is one of the major amyloidogenic proteins in systemic
amyloidosis, forms extracellular amyloid deposits in the systemic organs such as nerves …
amyloidosis, forms extracellular amyloid deposits in the systemic organs such as nerves …
Hereditary transthyretin amyloidosis: molecular basis and therapeutical strategies
MJM Saraiva - Expert reviews in molecular medicine, 2002 - cambridge.org
Transthyretin (TTR) is a transport protein for thyroid hormones and vitamin A and might have
an important role in the nervous system. However, TTR can undergo a conformational …
an important role in the nervous system. However, TTR can undergo a conformational …
Ultrastructure in transthyretin amyloidosis: from pathophysiology to therapeutic insights
H Koike, M Katsuno - Biomedicines, 2019 - mdpi.com
Transthyretin (TTR) amyloidosis is caused by systemic deposition of wild-type or variant
amyloidogenic TTR (ATTRwt and ATTRv, respectively). ATTRwt amyloidosis has …
amyloidogenic TTR (ATTRwt and ATTRv, respectively). ATTRwt amyloidosis has …
Transthyretin amyloidosis: an under-recognized neuropathy and cardiomyopathy
NJ Galant, P Westermark, JN Higaki… - Clinical …, 2017 - portlandpress.com
Transthyretin (TTR) amyloidosis (ATTR amyloidosis) is an underdiagnosed and important
type of cardiomyopathy and/or polyneuropathy that requires increased awareness within the …
type of cardiomyopathy and/or polyneuropathy that requires increased awareness within the …
Hereditary transthyretin amyloidosis: a comprehensive review with a focus on peripheral neuropathy
L Poli, B Labella, S Cotti Piccinelli, F Caria… - Frontiers in …, 2023 - frontiersin.org
Amyloidoses represent a group of diseases characterized by the pathological accumulation
in the extracellular area of insoluble misfolded protein material called “amyloid”. The …
in the extracellular area of insoluble misfolded protein material called “amyloid”. The …
Genetic testing improves identification of transthyretin amyloid (ATTR) subtype in cardiac amyloidosis
EE Brown, YZJ Lee, MK Halushka, C Steenbergen… - Amyloid, 2017 - Taylor & Francis
Amyloidosis is a group of conditions characterized by the accumulation of amyloid deposits
in various tissues. Among these disorders, ATTR amyloidosis occurs either with or without a …
in various tissues. Among these disorders, ATTR amyloidosis occurs either with or without a …
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