Stressful life experiences are likely etiological factors in sporadic forms of Alzheimer's
disease (AD). Many AD patients hypersecrete glucocorticoids (GCs), and their GC levels …

Several studies have linked stress with Alzheimer's disease (AD) vulnerability; however, the
mechanism remains to be fully elucidated. In the current paper, we investigated the role of …

Neurodegenerative diseases are characterized by an irreversible and progressive loss of
neuronal structure and function. While many alterations to normal cellular processes occur …

Because overactivation of the hypothalamic–pituitary–adrenal (HPA) axis occurs in
Alzheimer's disease (AD), dysregulation of stress neuromediators may play a mechanistic …

Exposure to chronic stress is frequently accompanied by cognitive and affective disorders in
association with neurostructural adaptations. Chronic stress was previously shown to trigger …

Various environmental and genetic factors influence the onset and progression of
Alzheimer's disease (AD). Dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis …

Chronic stress may be a risk factor for developing Alzheimer's disease (AD), but most
studies of the effects of stress in models of AD utilize acute adverse stressors of …

The etiology of the more common (sporadic) forms of Alzheimer's disease (AD) remains
unknown, although age is the most important risk factor. Nevertheless, interactions between …

Although chronic stress is known to be linked with memory and other neurological disorders,
little is known about the relationship between chronic stress and the onset or development of …

Recent clinical data have implicated chronic adverse stress as a potential risk factor in the
development of Alzheimer's disease (AD) and data also suggest that normal, physiological …