Carboplatin is a platinum based drug used in the treatment of several malignancies. Due to
poor cellular uptake, generally, a larger dose of drug is administered to achieve therapeutic …

Poor cellular uptake contributes to high dose requirement and limited therapeutic efficacy of
the platinum-based anticancer drug carboplatin. Delivery systems that can improve the …

Cisplatin is one of the most potent anticancer agent used in the treatment of various solid
tumors, however, its clinical use is limited due to severe adverse effects including …

Aims The study aimed to develop, characterize, and evaluate poly (ɛ-caprolactone)(PCL)
based nanoparticles for the sustained release behaviour of cytarabine and to investigate the …

Background and objective In a phase II clinical trial, carboplatin (CBDCA) displayed the
response rate of 19% equivalent to dacarbazine in the treatment of malignant melanoma …

The goal of the present study is to utilize cis-diamminedichloroplatinum (cisplatin) loaded
polymer nanoparticles (NPs) to give a controlled, extended, and local drug therapy for the …

The aim of this study is to investigate the feasibility and efficacy of PEC nanoparticles as
delivery system for cancer chemotherapy. Assembly of paclitaxel‐loaded nanoparticles with …

Objective: Today, cancer is still among the most common chronic diseases. Nanoparticular
drug delivery systems prepared with biocompatible and biodegradable polymers such as …

Polysorbate 80 (Tween 80) has been widely used as an emulsifier with excellent effects in
nanoparticles technology for biomedical applications. This work was thus triggered to …

Biodegradable poly (ε-caprolactone)/poly (ethylene glycol)(PCL/PEG) copolymer
nanoparticles showed potential application in drug delivery systems. In this article …