Regulation of galanin gene expression in the hypothalamic paraventricular nucleus of the obese Zucker rat by manipulation of dietary macronutrients

JG Mercer, CB Lawrence, T Atkinson - Molecular brain research, 1996 - Elsevier
Lean and obese male Zucker rats were fed high fat (72% of energy as fat), high
carbohydrate (66% of energy as carbohydrate) or intermediate diets for 4 weeks …

Critical effects of aging and nutritional state on hypothalamic neuropeptide Y and galanin gene expression in lean and genetically obese Zucker rats

M Jhanwar-Uniyal, SC Chua Jr - Molecular brain research, 1993 - Elsevier
We have investigated, by Northern blot analysis, the hypothalamic gene expression
[messenger RNA (mRNA)] of two appetite stimulating neuropeptides, neuropeptide Y (NPY) …

Obesity on a high-fat diet: role of hypothalamic galanin in neurons of the anterior paraventricular nucleus projecting to the median eminence

SF Leibowitz, A Akabayashi, J Wang - Journal of Neuroscience, 1998 - Soc Neuroscience
Previous studies have suggested that the peptide galanin (GAL) in the hypothalamus is
related to the preference of an animal for dietary fat. The present report investigates this …

Hypothalamic galanin: control by signals of fat metabolism

J Wang, A Akabayashi, HJ Yu, J Dourmashkin… - Brain research, 1998 - Elsevier
The peptide, galanin (GAL), is known to stimulate eating behavior, reduce energy
expenditure and affect the release of metabolic hormones. Further, the activity of this peptide …

Effects of diabetes and insulin on the expression of galanin-like peptide in the hypothalamus of the rat

GS Fraley, JM Scarlett, I Shimada, DN Teklemichael… - Diabetes, 2004 - Am Diabetes Assoc
Galanin-like peptide (GALP) is produced in a small population of neurons in the arcuate
nucleus of the hypothalamus, and leptin stimulates the hypothalamic expression of GALP …

Dietary preferences of Brattleboro rats correlated with an overexpression of galanin in the hypothalamus

M Odorizzi, JP Max, P Tankosic… - European Journal of …, 1999 - Wiley Online Library
Galanin (GAL) is a neuropeptide cosynthesized with vasopressin (AVP) in neurons of the
hypothalamo‐neurohypophysial system. It increases food intake when injected into the brain …

Galanin in the hypothalamus of fed and fasted lean and obese Zucker rats

B Beck, A Burlet, JP Nicolas, C Burlet - Brain research, 1993 - Elsevier
Abstract Galanin (GAL), a 29 aminoacid peptide, is widely distributed in the central nervous
system and especially in the hypothalamus. It strongly stimulates food intake when it is …

Galanin-containing neurons in the paraventricular nucleus: a neurochemical marker for fat ingestion and body weight gain.

A Akabayashi, JI Koenig, Y Watanabe… - Proceedings of the …, 1994 - National Acad Sciences
The physiological function of the peptide galanin (Gal) remains to be established. It is known
to exist in high concentrations within the hypothalamus and to modulate the secretion of …

Effect of inhibition of glucose and fat metabolism on galanin-R1 receptor mRNA levels in the rat hypothalamic paraventricular and supraoptic nuclei

O Gorbatyuk, T Hökfelt - Neuroreport, 1998 - journals.lww.com
USING in situ hybridization histochemistry we have studied the effect of glucose and fat
deprivation on galanin-R1 receptor (GAL-R1-R) mRNA levels in the rat paraventricular …

Galanin-like peptide gene expression in the hypothalamus and posterior pituitary of the obese fa/fa rat

J Saito, Y Ozaki, M Kawasaki, H Ohnishi, N Okimoto… - Peptides, 2004 - Elsevier
We examined the galanin-like peptide (GALP) gene expression in the arcuate nucleus
(ARC) and posterior pituitary (PP) in 6-and 18-week-old male obese fa/fa rats. GALP mRNA …