Phenotypic integration without modularity: testing hypotheses about the distribution of pleiotropic quantitative trait loci in a continuous space
CC Roseman, JP Kenny-Hunt, JM Cheverud - Evolutionary Biology, 2009 - Springer
Theories of phenotypic integration have relied heavily on the concept of modularity in order
to model the ways in which traits in an organism correlate and covary. Recent investigations …
to model the ways in which traits in an organism correlate and covary. Recent investigations …
THE GENETIC ARCHITECTURE OF PLEIOTROPIC RELATIONS AND
JM Cheverud - The character concept in evolutionary biology, 2000 - books.google.com
Patterns of morphological integration follow patterns of developmental and functional
relationship among traits. However, the genetic architecture underlying morphological …
relationship among traits. However, the genetic architecture underlying morphological …
Shared quantitative trait loci underlying the genetic correlation between continuous traits
KM Gardner, RG Latta - Molecular ecology, 2007 - Wiley Online Library
We review genetic correlations among quantitative traits in light of their underlying
quantitative trait loci (QTL). We derive an expectation of genetic correlation from the effects …
quantitative trait loci (QTL). We derive an expectation of genetic correlation from the effects …
Pleiotropic effects on mandibular morphology II: differential epistasis and genetic variation in morphological integration
JM Cheverud, TH Ehrich, TT Vaughn… - … Zoology Part B …, 2004 - Wiley Online Library
The evolution of morphological modularity through the sequestration of pleiotropy to sets of
functionally and developmentally related traits requires genetic variation in the relationships …
functionally and developmentally related traits requires genetic variation in the relationships …
Developmental integration and the evolution of pleiotropy
JM Cheverud - American Zoologist, 1996 - academic.oup.com
The different forms of morphological integration, developmental, functional, genetic, and
evolutionary are defined and their theoretical relationships explored. Quantitative genetic …
evolutionary are defined and their theoretical relationships explored. Quantitative genetic …
Quantitative trait loci and gene interaction: the quantitative genetics of metapopulations
CJ Goodnight - Heredity, 2000 - nature.com
Genetic population differentiation is typically viewed as differentiation of population means.
However, several theories of evolution and speciation postulate that populations …
However, several theories of evolution and speciation postulate that populations …
[PDF][PDF] Quantitative trait loci: individual gene effects on quantitative characters
JM Cheverud, E Routman - Journal of Evolutionary Biology, 1993 - academia.edu
Over the past few years great progress has been made in detecting and mapping genes of
major effect, including the genes responsible for cystic fibrosis. Huntington's chorea, and …
major effect, including the genes responsible for cystic fibrosis. Huntington's chorea, and …
Alleles versus mutations: Understanding the evolution of genetic architecture requires a molecular perspective on allelic origins
DL Remington - Evolution, 2015 - academic.oup.com
Perspectives on the role of large-effect quantitative trait loci (QTL) in the evolution of
complex traits have shifted back and forth over the past few decades. Different sets of …
complex traits have shifted back and forth over the past few decades. Different sets of …
Building developmental integration into functional systems: function-induced integration of mandibular shape
ML Zelditch, AR Wood, DL Swiderski - Evolutionary Biology, 2009 - Springer
The mammalian mandible is a developmentally modular but functionally integrated system.
Whether morphological integration can evolve to match the optimal pattern of functional …
Whether morphological integration can evolve to match the optimal pattern of functional …
Is the genotype-phenotype map modular?: a statistical approach using mouse quantitative trait loci data
JG Mezey, JM Cheverud, GP Wagner - Genetics, 2000 - academic.oup.com
Various theories about the evolution of complex characters make predictions about the
statistical distribution of genetic effects on phenotypic characters, also called the genotype …
statistical distribution of genetic effects on phenotypic characters, also called the genotype …
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