Nanoparticle-based delivery systems as emerging therapy in retinoblastoma: recent advances, challenges and prospects
AL Onugwu, OL Ugorji, CA Ufondu, SA Ihim… - Nanoscale …, 2023 - pubs.rsc.org
Retinoblastoma is the most common intraocular malignancy in children. The treatment of this
rare disease is still challenging in developing countries due to delayed diagnosis. The …
rare disease is still challenging in developing countries due to delayed diagnosis. The …
Nanotechnology for pediatric retinoblastoma therapy
E Russo, A Spallarossa, B Tasso, C Villa, C Brullo - Pharmaceuticals, 2022 - mdpi.com
Retinoblastoma is a rare, sometimes hereditary, pediatric cancer. In high-income countries
this disease has a survival rate approaching 100%, while in low-and middle-income …
this disease has a survival rate approaching 100%, while in low-and middle-income …
Management of retinoblastoma: opportunities and challenges
D Bhavsar, K Subramanian, S Sethuraman… - Drug …, 2016 - Taylor & Francis
Nano-delivery systems have significantly evolved over the last decade for the treatment of
cancer by enabling site-specific delivery and improved bioavailability. The widely …
cancer by enabling site-specific delivery and improved bioavailability. The widely …
Nanoparticle-mediated gene therapy as a novel strategy for the treatment of retinoblastoma
Over the last two decades, nanoparticulate delivery systems have revolutionized cancer
treatment by achieving target-specific delivery, enhanced bioavailability, and improved …
treatment by achieving target-specific delivery, enhanced bioavailability, and improved …
[HTML][HTML] Multi-functionalized nanomaterials and nanoparticles for diagnosis and treatment of retinoblastoma
Retinoblastoma is a rare type of cancer, and its treatment, as well as diagnosis, is
challenging, owing to mutations in the tumor-suppressor genes and lack of targeted …
challenging, owing to mutations in the tumor-suppressor genes and lack of targeted …
Advances in biomaterials for the treatment of retinoblastoma
Retinoblastoma is the most common primary intraocular malignancy in children. Although
traditional chemotherapy has shown some success in retinoblastoma management, there …
traditional chemotherapy has shown some success in retinoblastoma management, there …
Advancements in Nanosystems for Ocular Drug Delivery: A Focus on Pediatric Retinoblastoma
KY Wu, XC Wang, M Anderson, SD Tran - Molecules, 2024 - mdpi.com
The eye's complex anatomical structures present formidable barriers to effective drug
delivery across a range of ocular diseases, from anterior to posterior segment pathologies …
delivery across a range of ocular diseases, from anterior to posterior segment pathologies …
Nanoparticulate drug delivery to the retina
Retinal diseases, such as age-related macular degeneration and diabetic retinopathy, are
the leading causes of blindness worldwide. The mainstay of treatment for these blinding …
the leading causes of blindness worldwide. The mainstay of treatment for these blinding …
Retinoblastoma: An update on genetic origin, classification, conventional to next-generation treatment strategies
The most prevalent paediatric vision-threatening medical condition, retinoblastoma (RB),
has been a global concern for a long time. Several conventional therapies, such as systemic …
has been a global concern for a long time. Several conventional therapies, such as systemic …
Frontiers in the treatment of glioblastoma: Past, present and emerging
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …
research over the last several decades, the survival rates for GBM have not improved and …