Natural components continue to be an important source for the discovery and development
of novel anticancer agents. Polymethoxyflavones are a class of flavonoids found in citrus …

The aim of this study was to find the efficacy of 5-hydroxy 3′, 4′, 7-trimethoxyflavone
(HTMF), a flavonoid compound isolated from the medicinal plant Lippia nodiflora, in …

The fruit peel of Citrus species (Chenpi), particularly those of mandarin oranges, is a useful
source of food and medicine in China. Flavonoids from the citrus fruit peel are mainly …

The absence of progesterone receptors, estrogen receptors, and human epidermal growth
factor receptor-2 restricts the therapy choices for treating triple-negative breast cancer …

Background Flavones found in plants display various biological activities, including anti-
allergic, anti-viral, anti-inflammatory, anti-oxidation, and anti-tumor effects. In this study, we …

Background Nor-wogonin, a polyhydroxy flavone, has been shown to possess antitumor
activity. However, the mechanisms responsible for its antitumor activity are poorly studied …

Natural remedies have the potential to improve conventional cancer therapies and enhance
patient outcomes. Citrus polymethoxyflavone nobiletin has been demonstrated to have …

In the course of our search for new antitumor agents for breast cancer, novel flavone
derivatives were synthesized, characterized and examined for their antitumor activities …

Sesquiterpene lactones (SLs) are plant‐derived constituents that have been proved to have
potential antitumour activity. However, the intracellular molecular targets of SLs and the …

Triple negative breast cancer (TNBC) is a breast cancer subtype characterized by the
absence of estrogen receptor, progesterone receptor and human epidermal growth factor …