Management of infections caused by multidrug-resistant gram-negative pathogens: recent advances and future directions

M Bassetti, A Vena, DR Giacobbe… - Archives of medical …, 2021 - Elsevier
During the last decades, the isolation of multidrug-resistant Gram-negative (MDR-GN)
bacteria has dramatically increased worldwide and has been associated with significant …

[HTML][HTML] Treatment of infections due to MDR Gram-negative bacteria

M Bassetti, M Peghin, A Vena, DR Giacobbe - Frontiers in medicine, 2019 - frontiersin.org
The treatment of multidrug-resistant Gram-negative bacteria (MDR-GNB) infections in
critically ill patients presents many challenges. Since an effective treatment should be …

Patient specific risk stratification for antimicrobial resistance and possible treatment strategies in gram-negative bacterial infections

M Bassetti, A Carnelutti, M Peghin - Expert review of anti-infective …, 2017 - Taylor & Francis
Introduction: The isolation of multi-drug-resistant gram-negative (MDRGN) pathogens has
progressively increased worldwide and has been associated with important delays in the …

Multidrug-resistant gram-negative bacterial infections in the hospital setting: overview, implications for clinical practice, and emerging treatment options

E Cerceo, SB Deitelzweig, BM Sherman… - Microbial Drug …, 2016 - liebertpub.com
The increasing prevalence of infections due to multidrug-resistant (MDR) gram-negative
bacteria constitutes a serious threat to global public health due to the limited treatment …

[HTML][HTML] Trends, epidemiology, and management of multi-drug resistant gram-negative bacterial infections in the hospitalized setting

S Morris, E Cerceo - Antibiotics, 2020 - mdpi.com
The increasing prevalence of antibiotic resistance is a threat to human health, particularly
within vulnerable populations in the hospital and acute care settings. This leads to …

Emerging issues in the management of infections caused by multidrug-resistant gram-negative bacteria.

LB Rice - Cleveland Clinic journal of medicine, 2007 - europepmc.org
Accumulating evidence indicates that treating seriously ill infected patients with active
antibiotics early in the course of infection is critical to improving outcomes. The most …

Multidrug-resistant Gram-negative bacteria-resistant infections: epidemiology, clinical issues and therapeutic options

M Bassetti, D Pecori, M Peghin - Italian Journal of Medicine, 2016 - italjmed.org
In the last decade, we have witnessed a dramatic increase in the number of multidrug
resistant Gram-negative (MDRGN) bacterial pathogens, both in Italy and worldwide, with …

Multidrug-resistant gram-negative bacilli: infection control implications

A Adler, ND Friedman, D Marchaim - Infectious Disease Clinics, 2016 - id.theclinics.com
Enterobacter species, and Escherichia coli. Emergence of resistance to a widerange of
antibiotics among these common human pathogens places an enormous burden on …

Recent advances in the pharmacological management of infections due to multidrug-resistant Gram-negative bacteria

DR Giacobbe, M Mikulska, C Viscoli - Expert review of clinical …, 2018 - Taylor & Francis
Introduction: The emergence and diffusion of multidrug-resistant Gram-negative bacteria
(MDR-GNB) is an unprecedented threat, with prevalences as high as 10–50% being …

[HTML][HTML] Choice of therapeutic interventions and outcomes for the treatment of infections caused by multidrug-resistant gram-negative pathogens: a systematic review

SM Nørgaard, CS Jensen, J Aalestrup… - … Resistance & Infection …, 2019 - Springer
Background Antimicrobial resistance is an increasingly serious threat to public health, and
the increased occurrence of multidrug-resistant (MDR) bacteria is a concern in both high …