Abstract Background. The European Organization for Research and Treatment of Cancer
(EORTC) and the Mycosis Study Group (MSG) definition of invasive aspergillosis used in …

Aspergillus is a genus of fungi commonly found in all environments. Remarkably, only a few
species cause disease and equally remarkably, those same species cause multiple …

Background: Successful therapy of invasive aspergillosis is difficult, and the place of new
drugs is evolving. Earlier studies, with fewer patients, suggest itraconazole, an oral azole, is …

Invasive fungal disease of humans caused by species of the genus Aspergillus Micheli ex
Linnaeus has becomea significantand prevalent problem in contemporary medicine …

The experience of the Center for Disease Control Cooperative Mycoses Study with the use
of amphotericin B in the treatment of saprophytic forms of pulmonary aspergillosis was …

PURPOSE: Invasive aspergillosis in the immuno-compromised host is one of the most
difficult therapeutic problems. Itraconazole, a new oral triazole, is inhibitory as well as …

Eighty-seven patients with hematologic malignancies and invasive pulmonary aspergillosis
(IPA) were identified between 1982 and 1995. Of these, 39 underwent lung resection on the …

OBJECTIVE:: This study evaluated the clinical features and treatment outcomes in patients
with endogenous Aspergillus endophthalmitis. DESIGN:: The study design was a multicenter …

The development of newer antifungal drugs is creating new potential combination therapies
to combat the dismal mortality rate associated with invasive aspergillosis (IA). The efficacy of …

The incidence of invasive aspergillosis is markedly increasing, and mortality remains dismal.
Previously there were only 2 antifungals with activity against Aspergillus, but over the last …