Processing of semen by density gradient centrifugation selects spermatozoa with longer telomeres for assisted reproduction techniques

Q Yang, N Zhang, F Zhao, W Zhao, S Dai, J Liu… - Reproductive …, 2015 - Elsevier
The ends of eukaryotic chromosomes contain specialized chromatin structures called
telomeres, the length of which plays a key role in early human embryonic development …

[HTML][HTML] Semen preparation methods and sperm telomere length: density gradient centrifugation versus the swim up procedure

F Zhao, Q Yang, S Shi, X Luo, Y Sun - Scientific reports, 2016 - nature.com
Previous studies have shown that both density gradient centrifugation (DGC) and swim up
(SU) procedures can select spermatozoa with longer telomeres for assisted reproduction …

[HTML][HTML] Discordance between human sperm quality and telomere length following differential gradient separation/swim-up

AC Lopes, PF Oliveira, S Pinto, C Almeida… - Journal of Assisted …, 2020 - Springer
Background Strong evidence has suggested an important role of telomeres in meiosis,
fertilization, and embryo development. Purpose To determine if sperm telomere length (STL) …

Sperm telomere length in motile sperm selection techniques: A qFISH approach

R Lafuente, E Bosch‐Rue, J Ribas‐Maynou… - Andrologia, 2018 - Wiley Online Library
Several studies have associated telomere shortening with alterations in reproductive
function. The objective of the present study was to determine telomere length (TL) in …

[HTML][HTML] A single-cell assay for telomere DNA content shows increasing telomere length heterogeneity, as well as increasing mean telomere length in human …

DMF Antunes, KH Kalmbach, F Wang… - Journal of assisted …, 2015 - Springer
Purpose The effect of age on telomere length heterogeneity in men has not been studied
previously. Our aims were to determine the relationship between variation in sperm telomere …

Genomic fragmentation and extrachromosomal telomeric repeats impact assessment of telomere length in human spermatozoa: quantitative experiments and …

P Kurjanowicz, S Moskovtsev, C Librach - Human Reproduction, 2017 - academic.oup.com
ABSTRACT STUDY QUESTION Can differences in DNA isolation alter assessment of sperm
telomere length (spTL) and do they account for conflicting results in the literature on spTL …

[HTML][HTML] Telomere length in bovine sperm is related to the production of reactive oxygen species, but not to reproductive performance

J Ribas-Maynou, M Llavanera, Y Mateo-Otero, N Ruiz… - Theriogenology, 2022 - Elsevier
Over the last decades, selection in cattle has mainly been based on milk production rather
than on reproductive efficiency. While, when applied, focus on reproduction has involved …

Is telomere length a biomarker of sperm quality? A systematic review and meta‐analysis of observational studies

M Fernández de la Puente, A Salas‐Huetos… - …, 2024 - Wiley Online Library
Background Telomeres are essential for the integrity of chromosome ends during cell
division and their involvement in different processes linked to aging has been established …

Relationship between sperm telomere length and sperm quality in infertile men

Z Darmishonnejad, F Zarei‐Kheirabadi… - Andrologia, 2020 - Wiley Online Library
Telomeres, noncoding and repetitive DNA sequences play a significant function in
chromatin integrity. Telomere length is age‐dependent in somatic cells, while it increases in …

Telomere Distribution in Human Sperm Heads and Its Relation to Sperm Nuclear Morphology: A New Marker for Male Factor Infertility?

KJ Turner, EM Watson, BM Skinner… - International Journal of …, 2021 - mdpi.com
Infertility is a problem affecting an increasing number of couples worldwide. Currently,
marker tests for male factor infertility are complex, highly technical and relatively subjective …