Macromolecules enter or leave the nucleus by using nuclear localization signals (NLS), or
nuclear export signals (NES), respectively. Different types of NLS and NES are recognized …

Molecules enter and exit the nucleus of eukaryotic cells through aqueous channels formed
in the nuclear envelope by nuclear pore complexes (NPC). Proteins entering or leaving the …

Background: The transport of macromolecules between the nucleus and cytoplasm is an
energy-dependent process. Substrates are translocated across the nuclear envelope …

Nuclear import and export signals on macromolecules mediate directional, receptor-driven
transport through the nuclear pore complex (NPC) by a process that is suggested to involve …

Nuclear transport is an energy-dependent process mediated by saturable receptors. Import
and export receptors are thought to recognize and bind to nuclear localization signals or …

In eukaryotes, the nuclear membrane provides a physical barrier to the passive diffusion of
macromolecules from and into the cytoplasm. Nucleocytoplasmic traffic occurs through …

Transport of proteins into and out of the nucleus occurs through nuclear pore complexes
(NPC). A heterodimeric protein complex, composed of karyopherin a and β (or importin α …

Importin β family transport receptors shuttle between the nucleus and the cytoplasm and
mediate transport of macromolecules through nuclear pore complexes (NPCs). The …

The nuclear import of proteins through nuclear pore complexes (NPCs) illustrates how a
complex biological function can be generated by a spatially and temporally organized cycle …

The trafficking of protein and RNA cargoes between the cytoplasm and the nucleus of
eukaryotic cells, which is a major pathway involved in cell regulation, is mediated by nuclear …