Transcriptional hallmarks of heterogeneous neural stem cell niches of the subventricular zone

K Azim, A Hurtado-Chong, B Fischer, N Kumar… - Stem …, 2015 - academic.oup.com
Throughout postnatal life in mammals, neural stem cells (NSCs) are located in the
subventricular zone (SVZ) of the lateral ventricles. The greatest diversity of neuronal and …

[PDF][PDF] HOPX defines heterogeneity of postnatal subventricular zone neural stem cells

S Zweifel, G Marcy, QL Guidice, D Li, C Heinrich… - Stem cell reports, 2018 - cell.com
The largest diversity of neural lineages generated from the subventricular zone (SVZ) occurs
early after birth and is regulated in a spatiotemporal manner depending on the expression of …

[HTML][HTML] Identity and nature of neural stem cells in the adult human subventricular zone

S Baig, J Nadaf, R Allache, PU Le, M Luo, A Djedid… - Iscience, 2024 - cell.com
The existence of neural stem cells (NSCs) in adult human brain neurogenic regions remains
unresolved. To address this, we created a cell atlas of the adult human subventricular zone …

High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging

XP Xie, DR Laks, D Sun, A Poran… - Proceedings of the …, 2020 - National Acad Sciences
Adult neural stem cells (NSC) serve as a reservoir for brain plasticity and origin for certain
gliomas. Lineage tracing and genomic approaches have portrayed complex underlying …

Molecular diversity subdivides the adult forebrain neural stem cell population

C Giachino, O Basak, S Lugert, P Knuckles… - Stem …, 2014 - academic.oup.com
Neural stem cells (NSCs) in the ventricular domain of the subventricular zone (V-SVZ) of
rodents produce neurons throughout life while those in humans become largely inactive or …

Neural stem cell heterogeneity through time and space in the ventricular-subventricular zone

G Rushing, RA Ihrie - Frontiers in biology, 2016 - Springer
Background The origin and classification of neural stem cells (NSCs) has been a subject of
intense investigation for the past two decades. Efforts to categorize NSCs based on their …

Heterogeneity in ventricular zone neural precursors contributes to neuronal fate diversity in the postnatal neocortex

EK Stancik, I Navarro-Quiroga, R Sellke… - Journal of …, 2010 - Soc Neuroscience
The recent discovery of short neural precursors (SNPs) in the murine neocortical ventricular
zone (VZ) challenges the widely held view that radial glial cells (RGCs) are the sole …

Chromatin-based epigenetics of adult subventricular zone neural stem cells

G Gonzales-Roybal, DA Lim - Frontiers in genetics, 2013 - frontiersin.org
In specific regions of the adult mammalian brain, neural stem cells (NSCs) generate new
neurons throughout life. Emerging evidence indicate that chromatin-based transcriptional …

Characterization of the ventricular-subventricular stem cell niche during human brain development

AM Coletti, D Singh, S Kumar, TN Shafin… - …, 2018 - journals.biologists.com
Human brain development proceeds via a sequentially transforming stem cell population in
the ventricular-subventricular zone (V-SVZ). An essential, but understudied, contributor to V …

[PDF][PDF] Single-cell analysis of regional differences in adult V-SVZ neural stem cell lineages

D Mizrak, HM Levitin, AC Delgado, V Crotet, J Yuan… - Cell reports, 2019 - cell.com
The ventricular-subventricular zone (V-SVZ) harbors adult neural stem cells. V-SVZ neural
stem cells exhibit features of astrocytes, have a regional identity, and depending on their …