Mitogenic stimulation of resting T cells causes rapid phosphorylation of the transcription factor LSF and increased DNA-binding activity.
JL Volker, LE Rameh, Q Zhu, J DeCaprio… - Genes & …, 1997 - genesdev.cshlp.org
The mammalian transcription factor LSF (CP2/LBP-1c) binds cellular promoters modulated
by cell growth signals. We demonstrate here that LSF-DNA-binding activity is strikingly …
by cell growth signals. We demonstrate here that LSF-DNA-binding activity is strikingly …
Mammalian transcription factor LSF is a target of ERK signaling
Z Pagon, J Volker, GM Cooper… - Journal of cellular …, 2003 - Wiley Online Library
LSF is a mammalian transcription factor that is rapidly and quantitatively phosphorylated
upon growth induction of resting, peripheral human T cells, as assayed by a reduction in its …
upon growth induction of resting, peripheral human T cells, as assayed by a reduction in its …
One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs
MK Shirra, Q Zhu, HC Huang, D Pallas… - Molecular and cellular …, 1994 - Taylor & Francis
The transcription factor LSF, identified as a HeLa protein that binds the simian virus 40 late
promoter, recognizes direct repeats with a center-to-center spacing of 10 bp. The …
promoter, recognizes direct repeats with a center-to-center spacing of 10 bp. The …
LSF and NTF-1 share a conserved DNA recognition motif yet require different oligomerization states to form a stable protein-DNA complex
MK Shirra, U Hansen - Journal of Biological Chemistry, 1998 - ASBMB
The mammalian transcription factor LSF (also known as CP2 and LBP-1c) binds as a homo-
oligomer to directly repeated elements in viral and cellular promoters. LSF and …
oligomer to directly repeated elements in viral and cellular promoters. LSF and …
Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF
J Veljkovic, U Hansen - Gene, 2004 - Elsevier
Transcriptional regulation in mammalian cells is driven by a complex interplay of multiple
transcription factors that respond to signals from either external or internal stimuli. A single …
transcription factors that respond to signals from either external or internal stimuli. A single …
Phosphorylation by Cyclin C/Cyclin-Dependent Kinase 2 following Mitogenic Stimulation of Murine Fibroblasts Inhibits Transcriptional Activity of LSF during G1 …
UH Saxena, CMH Powell, JK Fecko… - … and Cellular Biology, 2009 - Taylor & Francis
Transcription factor LSF is required for progression from quiescence through the cell cycle,
regulating thymidylate synthase (Tyms) expression at the G1/S boundary. Given the constant …
regulating thymidylate synthase (Tyms) expression at the G1/S boundary. Given the constant …
Developmental regulation of lck gene expression in T lymphocytes.
RS Wildin, AM Garvin, S Pawar, DB Lewis… - The Journal of …, 1991 - rupress.org
In the mouse and human, mRNA transcripts encoding the lymphocyte-specific protein
tyrosine kinase p56lck are derived from two separate promoters resulting in heterogeneity in …
tyrosine kinase p56lck are derived from two separate promoters resulting in heterogeneity in …
[HTML][HTML] Activation of RNA polymerase II transcription by the specific DNA-binding protein LSF. Increased rate of binding of the basal promoter factor TFIIB.
R Sundseth, U Hansen - Journal of Biological Chemistry, 1992 - Elsevier
While the components of the initiation complex at an RNA polymerase II basal promoter
have been well characterized, few mechanistic studies have focused on how upstream DNA …
have been well characterized, few mechanistic studies have focused on how upstream DNA …
Functional dissection of the murine lck distal promoter.
RS Wildin, HU Wang, KA Forbush… - Journal of immunology …, 1995 - journals.aai.org
The lymphocyte-specific proto-oncogene lck is transcribed from two developmentally
regulated, independently functioning promoters. The proximal promoter is used in …
regulated, independently functioning promoters. The proximal promoter is used in …
The LSP1 gene is expressed in cultured normal and transformed mouse macrophages
J Jongstra, ME Ittel, NN Iscove, G Brady - Molecular immunology, 1994 - Elsevier
The mouse LSP1 protein is an F-actin binding protein initially isolated as a cDNA from the
BALB/c pre-B cell line 220.2. Its expression pattern is highly restricted. Only lymphocytes …
BALB/c pre-B cell line 220.2. Its expression pattern is highly restricted. Only lymphocytes …