Several cytochromes P450 (CYPs) are not only located in the endoplasmic reticulum but
also within mitochondria. One such CYP is CYP2E1 which metabolizes numerous …

Amiodarone (AD) and its major metabolite, desethylamiodarone (desethylAD), are both
phospholipogenic. The present study was undertaken to evaluate the comparative …

Chronic administration of amiodarone (AMIO), widely used by clinicians for the treatment of
therapy-resistant cardiac arrhythmias, is frequently associated with serious side-effects …

Amiodarone (AM) is an efficacious antidysrhythmic agent that can cause numerous adverse
effects, including potentially life-threatening pulmonary fibrosis. The current study was …

Amiodarone (AM) is a potent and efficacious antidysrhythmic agent that can cause
potentially life-threatening pulmonary fibrosis. Vitamin E has been demonstrated to …

Amiodarone is the most promising drug in the treatment of life-threatening ventricular
tachyarrhythmias in patients with significant structural heart disease. The pharmacologic …

Dronedarone, an antiarrhythmic drug, has been marketed as an alternative to amiodarone.
The use of dronedarone has been associated with severe liver injury; however, the …

Cholestasis has been reported as a rare presentation among patients with severe liver injury
secondary to amiodarone hepatic toxicity. We report an unusual case of amiodarone …

Diets high in polyunsaturated fatty acids (PUFA) are important for the development of
alcoholic liver injury. The goal of this report was to characterize toxicity by arachidonic acid …

Amiodarone (AMIO), a potent antiarrhythmic drug, is clinically widely used despite its
frequent side effects after chronic administration. These side effects coincide with an …