Aging is inevitably associated with a progressive loss of muscle mass and strength, a
condition also known as sarcopenia of aging. Although the precise mechanisms underlying …

The loss of muscle mass and strength with aging, also referred to as sarcopenia of aging, is
a highly prevalent condition among older adults and predicts several adverse outcomes …

Skeletal muscle aging is associated with a decline in motor function and loss of muscle
mass-a condition known as sarcopenia. The underlying mechanisms that drive this …

Skeletal myocyte atrophy and death contribute to sarcopenia, a condition associated with
normal aging. By 80 years of age, it is estimated that humans generally lose 30–40% of …

Sarcopenia may be partly due to a loss in total fiber number by apoptosis. We have
investigated age-related alterations in the mitochondria-mediated pathway leading to …

Primary aging is the progressive and inevitable process of bodily deterioration during
adulthood. In skeletal muscle, primary aging causes defective mitochondrial energetics and …

Sarcopenia refers to age-related loss of muscle mass and function. Several age-related
changes occur in skeletal muscle including a decrease in myofiber size and number and a …

Apoptosis is a highly conserved type of cell death that plays a critical role in tissue
homeostasis and disease-associated processes. Skeletal muscle is unique with respect to …

Sarcopenia, the age‐related loss of muscle mass and strength, is linked to a range of
adverse outcomes, such as impaired physical performance, cognitive function, and mortality …

Sarcopenia, the loss of muscle mass and function, is a common feature of aging and impacts
on individual health and quality of life. Several cellular mechanisms have been involved in …