As a group of cytokines, interferons are the first line of defense in the antiviral immunity. In
this study, Siberian tiger IFN-β (PtIFN-β) and IFN-γ (PtIFN-γ) were successfully amplified …

Interferon has a broad-spectrum of antiviral effects and represents an ideal choice for the
development of antiviral drugs. Nonetheless, information about alpha interferon (IFN-α) is …

Type I interferons (IFNs) are critical cytokines for the establishment of antiviral status in fish,
amphibian, avian and mammal, but the knowledge on type I IFNs is rather limited in reptile …

Recently, an original research discovers a new type of interferon (IFN) system in jawed
vertebrates, including type IV IFN (IFN-υ or IFNU) and its receptors (IFN-υR1 and IL-10R2) …

Interferons, as the first line of defense against the viral infection, play an important role in
innate immune responses. Type III interferon (IFN-λ) was a newly identified member of IFN …

Interferon-Epsilon (IFNε) is a type of interferon, a protein that plays a role in the immune
response to viral infections. This study is aimed at examining the molecular evolution of the …

Interferon (IFN) has a high clinical application prospect in the prevention and treatment of
viral diseases. In order to study and apply the IFN-α of forest musk deer (FMD), nine IFN-α …

Type III interferons (IFN-λ1/λ2/λ3, also known as IL-29/28A/28B, and IFN-λ4) are a recently
discovered interferon group. In this study, we first identified the Chinese goose IFN-λ (goIFN …

Abstract Interferon regulatory factor 1 (IRF1) is considered to be a vital regulator of antiviral
immune responses, and the knowledge on functions of IRF1 in antiviral defense is rather …

Interferon (IFN) is thought to play an important role in the vertebrate immune system, but
systemic knowledge of IFN evolution has yet to be elucidated. To evaluate the phylogenic …