Adenylyl cyclase type 9 gene polymorphisms are associated with asthma and allergy in Brazilian children
HMP Teixeira, NM Alcantara-Neves, M Barreto… - Molecular …, 2017 - Elsevier
Asthma is a chronic inflammatory disease of the respiratory tract. This heterogeneous
disease is caused by the interaction of interindividual genetic variability and environmental …
disease is caused by the interaction of interindividual genetic variability and environmental …
Polymorphisms in the DAD1 and OXA1L genes are associated with asthma and atopy in a South American population
A de Oliveira Pires, G de Almeida Queiroz… - Molecular …, 2018 - Elsevier
Atopic asthma, which is characterized by the chronic inflammation and morbidity of airways,
is a disease of great complexity, and multiple genetic and environmental factors are involved …
is a disease of great complexity, and multiple genetic and environmental factors are involved …
Single nucleotide polymorphisms predisposing to asthma in children of Mauritian Indian and Chinese Han ethnicity
K Ramphul, J Lv, L Hua, QH Liu, DZ Fang… - Brazilian Journal of …, 2014 - SciELO Brasil
Our objective was to investigate the distributions of six single nucleotide polymorphisms
(SNPs) MS4A2 E237G, MS4A2 C-109T, ADRB2 R16G, IL4RA I75V, IL4 C-590T, and IL13 …
(SNPs) MS4A2 E237G, MS4A2 C-109T, ADRB2 R16G, IL4RA I75V, IL4 C-590T, and IL13 …
PDE4D gene variants and haplotypes are associated with asthma and atopy in Brazilian children
H dos Santos Silva, HMP Teixeira, LG da Silva Gomes… - Immunobiology, 2023 - Elsevier
Abstract PDE4D (Phosphodiesterase 4D) gene encodes a hydrolase of cyclic AMP. PDE4D
genetic variants have been associated with asthma susceptibility. Therefore, this study …
genetic variants have been associated with asthma susceptibility. Therefore, this study …
Polymorphisms in recent GWA identified asthma genes CA10, SGK493, and CTNNA3 are associated with disease severity and treatment response in childhood …
P Perin, U Potočnik - Immunogenetics, 2014 - Springer
Recent genome-wide association studies (GWAs) have identified several new genetic risk
factors for asthma; however, their influence on disease behavior and treatment response is …
factors for asthma; however, their influence on disease behavior and treatment response is …
Association Between CD14 Polymorphism (−1145G/A) and Childhood Bronchial Asthma
Polymorphisms in the promoter region of CD14 gene have been associated with asthma
and atopy although the findings between cohorts have not been uniform. We aimed at …
and atopy although the findings between cohorts have not been uniform. We aimed at …
From expression pattern to genetic association in asthma and asthma-related phenotypes
VT Vaillancourt, M Bordeleau, M Laviolette… - BMC Research …, 2012 - Springer
Background Asthma is a complex disease characterized by hyperresponsiveness,
obstruction and inflammation of the airways. To date, several studies using different …
obstruction and inflammation of the airways. To date, several studies using different …
Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between β-agonist and corticosteroid pathways
KG Tantisira, KM Small, AA Litonjua… - Human molecular …, 2005 - academic.oup.com
In asthma, the response to β-agonists acting at β2-adrenergic receptors (β2AR) displays
extensive interindividual variation. One effector for airway β2AR, adenylyl cyclase type 9 …
extensive interindividual variation. One effector for airway β2AR, adenylyl cyclase type 9 …
Significant association of cyclin D1 promoter genotypes with asthma susceptibility in Taiwan
Background/Aim: The molecular mechanisms underlying the association between cell cycle
and asthma are poorly understood, and cyclin D1 (CCND1) is found to be upregulated in …
and asthma are poorly understood, and cyclin D1 (CCND1) is found to be upregulated in …
Polymorphisms in DENND1B gene are associated with asthma and atopy phenotypes in Brazilian children
BSD Fiuza, MJ Silva, NM Alcântara-Neves… - Molecular …, 2017 - Elsevier
Asthma is a heterogeneous disease associated with a complex basis involving
environmental factors and individual variabilities. The DENN Domain Containing 1B …
environmental factors and individual variabilities. The DENN Domain Containing 1B …