Since its invention in the 1940s, the positive pressure ventilator has always been known to
have both risks and benefits. Although mechanical ventilation is unquestionably lifesaving …

Acute hypoxemic respiratory failure (AHRF) is the most common organ failure and cause of
admission to the intensive care unit (ICU) among patients with COVID-19. As with all forms …

1. Perkins GD, Ji C, Connolly BA, et al; RECOVERY-RS Collaborators. Effect of noninvasive
respiratory strategies on intubation or mortality among patients with acute hypoxemic …

The end date for this most recent search update for our living systematic review (1) is 7 June
2020. We found 6 new citations that met eligibility for inclusion in our review addressing …

Acute respiratory distress syndrome (ARDS) can originate from either the gas or vascular
side of the alveolus. Although the portal for coronavirus disease 2019 (COVID-19) is …

The optimal mode of respiratory support for individuals with severe coronavirus disease
2019 (COVID-19) before invasive mechanical ventilation (IMV) is currently a subject of much …

Non-invasive respiratory strategies (NIRS) include noninvasive ventilation (NIV) and high-
flow nasal cannula (HFNC). Although neither are invasive, the physiological effects of NIV …

In his book “Of the Epidemics” Hippocrates advises physicians that they must “have two
special objects in view with regard to disease, namely, to do good or to do no harm”(1) …

Importance Continuous positive airway pressure (CPAP) and high-flow nasal oxygen
(HFNO) have been recommended for acute hypoxemic respiratory failure in patients with …

High-flow nasal oxygen (HFNO) and non-invasive ventilation (NIV) have been used to
manage early acute hypoxemic respiratory failure (AHRF) caused by COVID-19. As there is …