Biomaterial strategies for selective immune tolerance: advances and gaps
ST Carey, C Bridgeman, CM Jewell - Advanced Science, 2023 - Wiley Online Library
Autoimmunity and allergies affect a large number of people across the globe. Current
approaches to these diseases target cell types and pathways that drive disease, but these …
approaches to these diseases target cell types and pathways that drive disease, but these …
Biomaterial-based approaches to engineering immune tolerance
AE Emerson, EM Slaby, SC Hiremath… - Biomaterials Science, 2020 - pubs.rsc.org
The development of biomaterial-based therapeutics to induce immune tolerance holds great
promise for the treatment of autoimmune diseases, allergy, and graft rejection in …
promise for the treatment of autoimmune diseases, allergy, and graft rejection in …
Cell and biomaterial delivery strategies to induce immune tolerance
BL Scotland, JR Shaw, S Dharmaraj, N Caprio… - Advanced Drug Delivery …, 2023 - Elsevier
The prevalence of immune-mediated disorders, including autoimmune conditions and
allergies, is steadily increasing. However, current therapeutic approaches are often non …
allergies, is steadily increasing. However, current therapeutic approaches are often non …
Tissue‐Targeted Drug Delivery Strategies to Promote Antigen‐Specific Immune Tolerance
Y Rui, HB Eppler, AA Yanes… - Advanced healthcare …, 2023 - Wiley Online Library
During autoimmunity or organ transplant rejection, the immune system attacks host or
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …
Engineering immune tolerance with biomaterials
Autoimmune diseases, rejection of transplanted organs and grafts, chronic inflammatory
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …
[PDF][PDF] Engineering tolerance using biomaterials to target and control antigen presenting cells
LH Tostanoski, EA Gosselin, CM Jewell - Discov. Med, 2016 - jewell.umd.edu
Autoimmune diseases occur when cells of the adaptive immune system incorrectly
recognize and attack “self” tissues. Importantly, the proliferation and differentiation of these …
recognize and attack “self” tissues. Importantly, the proliferation and differentiation of these …
In vivo reprogramming of immune cells: technologies for induction of antigen-specific tolerance
Technologies that induce antigen-specific immune tolerance by mimicking naturally
occurring mechanisms have the potential to revolutionize the treatment of many immune …
occurring mechanisms have the potential to revolutionize the treatment of many immune …
Biomaterial strategies for immunomodulation
Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …
importance for diverse biomedical applications, such as the development of new vaccines …
[HTML][HTML] Targeted modulation of immune cells and tissues using engineered biomaterials
P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
Biomaterials-mediated engineering of the immune system
C Backlund, S Jalili-Firoozinezhad… - Annual review of …, 2023 - annualreviews.org
Modulation of the immune system is an important therapeutic strategy in a wide range of
diseases, and is fundamental to the development of vaccines. However, optimally safe and …
diseases, and is fundamental to the development of vaccines. However, optimally safe and …