Highlights•Biomaterials can potentially improve the safety and efficacy of cancer
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …

The immune system has remarkable capabilities to combat disease with exquisite selectivity.
This feature has enabled vaccines that provide protection for decades and, more recently …

Autoimmunity, allergy, and transplant rejection are a collection of chronic diseases that are
currently incurable, drastically decrease patient quality of life, and consume considerable …

The discovery of immune checkpoint blockade has revolutionized the field of immuno‐
oncology and established the foundation for developing various new therapies that can …

Breakthroughs in materials engineering have accelerated the progress of immunotherapy in
preclinical studies. The interplay of chemistry and materials has resulted in improved …

A cure for type 1 diabetes (T1D) would help millions of people worldwide but remains
elusive to date. Tolerogenic vaccines and β-cell replacement therapy are complementary …

Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Biomaterials are widely used for various medical purposes, for instance, implants, tissue
engineering, medical devices, and drug delivery systems. Natural biomaterials can be …

Adoptive immunotherapies based on the transfer of functional immune cells hold great
promise in treating a wide range of malignant diseases, especially cancers, autoimmune …

Vaccines and immunotherapies have provided enormous improvements for public health,
but there are fundamental disconnects between where most studies are performed—in cell …