Recently, biomaterial scientists have married materials engineering and immunobiology to
conceptualize new immunomodulatory materials. This special class of biomaterials can …

Despite the success of vaccines in preventing many infectious diseases, effective vaccines
against pathogens with ongoing challenges—such as HIV, malaria, and tuberculosis …

The immune system is the key target for vaccines and immunotherapeutic approaches
aimed at blunting infectious diseases, cancer, autoimmunity, and implant rejection …

Activation of immune cells is an essential process in innate and adaptive immunity. A high
number of immune cell activation pathways have been discovered, which are stimulated via …

The use of biomaterials for tissue engineering and regenerative medicine applications has
increased dramatically over recent years. However, the clinical uptake of a wide variety of …

T cells are often referred to as the 'guided missiles' of our immune system because of their
capacity to traffic to and accumulate at sites of infection or disease, destroy infected or …

Impairment of immune tolerance might cause autologous tissue damage or overactive
immune response against non-pathogenic molecules. Although autoimmune disease and …

© 2015 Macmillan Publishers Limited. All rights reserved vaccines and adjuvants. Self-
assembled nanoparticles comprising virus-derived and engineered proteins are the basis of …

The immune system has long been recognized to play a critical role in the host defense
against pathogens, foreign bodies, and the tissue healing response following injury. More …

Immunotherapy is a promising treatment modality for cancer as it can promote specific and
durable anti-cancer responses. However, limitations to current approaches remain …