Epstein–Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism

OG Thomas, A Rickinson… - Clinical & Translational …, 2023 - Wiley Online Library
Abstract The link between Epstein–Barr virus (EBV) and multiple sclerosis (MS) has puzzled
researchers since it was first discovered over 40 years ago. Until that point, EBV was …

MINI-review of Epstein-Barr virus involvement in multiple sclerosis etiology and pathogenesis

F Aloisi, AH Cross - Journal of Neuroimmunology, 2022 - Elsevier
Epstein-Barr virus (EBV) is the infectious agent that shows the strongest association with
multiple sclerosis (MS). EBV is a ubiquitous double stranded DNA herpes virus that …

[HTML][HTML] Altered immune response to the epstein–barr virus as a prerequisite for multiple sclerosis

F Läderach, C Münz - Cells, 2022 - mdpi.com
Strong epidemiologic evidence links Epstein–Barr virus (EBV) infection and its altered
immune control to multiple sclerosis (MS) development. Clinical MS onset occurs years after …

EBV in MS: guilty by association?

JD Lünemann, C Münz - Trends in immunology, 2009 - cell.com
Epstein–Barr Virus (EBV) is one of the most successful human viruses, infecting more than
90% of the adult population worldwide and persisting for the lifetime of the host. Individuals …

The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review

K Ruprecht - Expert review of clinical immunology, 2020 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system. While its exact etiology is unknown, it is generally believed that MS …

Viral pathophysiology of multiple sclerosis: A role for Epstein-Barr virus infection?

AH Maghzi, M Marta, I Bosca, M Etemadifar, R Dobson… - Pathophysiology, 2011 - Elsevier
Multiple sclerosis (MS) is the most common inflammatory demyelinating and degenerative
disease of the CNS. The cause of MS is unknown but environmental risk factors are …

From bedside to bench: how existing therapies inform the relationship between Epstein–Barr virus and multiple sclerosis

Z Dyer, D Tscharke, I Sutton… - Clinical & translational …, 2023 - Wiley Online Library
Therapy for relapsing–remitting multiple sclerosis (MS) has advanced dramatically despite
incomplete understanding of the cause of the condition. Current treatment involves inducing …

Epstein–Barr virus and multiple sclerosis: association or causation?

J Pakpoor, G Giovannoni… - Expert review of …, 2013 - Taylor & Francis
Multiple sclerosis (MS) is a multifactorial disease in which both genetic and environmental
factors and their interactions underlie causation. The current evidence base supports a …

[HTML][HTML] Epstein–Barr virus in multiple sclerosis: theory and emerging immunotherapies

A Bar-Or, MP Pender, R Khanna, L Steinman… - Trends in molecular …, 2020 - cell.com
New treatments for multiple sclerosis (MS) focused on B cells have created an atmosphere
of excitement in the MS community. B cells are now known to play a major role in disease …

Epstein–Barr virus and multiple sclerosis

M Salvetti, G Giovannoni, F Aloisi - Current opinion in neurology, 2009 - journals.lww.com
Epstein–Barr virus and multiple sclerosis : Current Opinion in Neurology Epstein–Barr virus
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