Prediction of peptide-MHC binding using profiles
PA Reche, EL Reinherz - Immunoinformatics: predicting immunogenicity in …, 2007 - Springer
Prediction of peptide binding to major histocompatibility complex (MHC) molecules is a
basis for anticipating T-cell epitopes. Peptides that bind to a given MHC molecule are …
basis for anticipating T-cell epitopes. Peptides that bind to a given MHC molecule are …
Prediction of MHC class I binding peptides using profile motifs
PA Reche, JP Glutting, EL Reinherz - Human immunology, 2002 - Elsevier
Peptides that bind to a given major histocompatibility complex (MHC) molecule share
sequence similarity. Therefore, a position specific scoring matrix (PSSM) or profile derived …
sequence similarity. Therefore, a position specific scoring matrix (PSSM) or profile derived …
[HTML][HTML] Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
J Salomon, DR Flower - BMC bioinformatics, 2006 - Springer
Background Modelling the interaction between potentially antigenic peptides and Major
Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell …
Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell …
Automated benchmarking of peptide-MHC class I binding predictions
Motivation: Numerous in silico methods predicting peptide binding to major
histocompatibility complex (MHC) class I molecules have been developed over the last …
histocompatibility complex (MHC) class I molecules have been developed over the last …
Examining the independent binding assumption for binding of peptide epitopes to MHC-I molecules
Motivation: Various methods have been proposed to predict the binding affinities of peptides
to Major Histocompatibility Complex class I (MHC-I) molecules based on experimental …
to Major Histocompatibility Complex class I (MHC-I) molecules based on experimental …
Predicting peptide binding to Major Histocompatibility Complex molecules
WWP Liao, JW Arthur - Autoimmunity reviews, 2011 - Elsevier
The Major Histocompatibility Complex (MHC) constitutes an important part of the human
immune system. During infection, pathogenic proteins are processed into peptide fragments …
immune system. During infection, pathogenic proteins are processed into peptide fragments …
A critical cross-validation of high throughput structural binding prediction methods for pMHC
T-cells recognize antigens via their T-cell receptors. The major histocompatibility complex
(MHC) binds antigens in a specific way, transports them to the surface and presents the …
(MHC) binds antigens in a specific way, transports them to the surface and presents the …
A structure-based approach for prediction of MHC-binding peptides
Y Altuvia, H Margalit - Methods, 2004 - Elsevier
Identification of immunodominant peptides is the first step in the rational design of peptide
vaccines aimed at T-cell immunity. The advances in sequencing techniques and the …
vaccines aimed at T-cell immunity. The advances in sequencing techniques and the …
[HTML][HTML] Quantitative prediction of mouse class I MHC peptide binding affinity using support vector machine regression (SVR) models
W Liu, X Meng, Q Xu, DR Flower, T Li - BMC bioinformatics, 2006 - Springer
Background The binding between peptide epitopes and major histocompatibility complex
proteins (MHCs) is an important event in the cellular immune response. Accurate prediction …
proteins (MHCs) is an important event in the cellular immune response. Accurate prediction …
[HTML][HTML] Strength in numbers: achieving greater accuracy in MHC-I binding prediction by combining the results from multiple prediction tools
Background Peptides derived from endogenous antigens can bind to MHC class I
molecules. Those which bind with high affinity can invoke a CD8+ immune response …
molecules. Those which bind with high affinity can invoke a CD8+ immune response …
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