The antitumor activity of the organometallic ruthenium (II)− arene complexes, RuCl2 (η6-
arene)(PTA),(arene= p-cymene, toluene, benzene, benzo-15-crown-5, 1-ethylbenzene-2, 3 …

Targeting protein–protein interactions (PPIs) offers tantalizing opportunities for therapeutic
intervention for the treatment of human diseases. Modulating PPI interfaces with organic …

A series of novel ruthenium (II) arene RAPTA type derivatives (arene= cymene,
hexamethylbenzene) containing curcumin-based ligands (curcH= curcumin, bdcurcH …

A suitable method for the synthesis of ruthenium (II) arene benzhydrazone complexes (1–6)
of the general formula [(η6-arene) Ru (L) Cl](arene-benzene or p-cymene; L-monobasic …

Ruthenium complexes with bioactive ligands are becoming promising substitutes for
platinum complexes due to their precise action against various cancers. In the present study …

A library of over 20 cycloplatinated compounds of the type [Pt (dmba-R) LCl](dmba-R= C, N-
dimethylbenzylamine-like ligand; R being MeO, Me, H, Br, F, CF3, and NO2 substituents in …

The introduction of multifunctionalities for tumour targeting is becoming a popular strategy
toward the development of new therapeutic agents. In particular, the multifaceted potential of …

RuII (η6-arene) compounds carrying bioactive flavonol ligands have shown promising
anticancer activity against tumor cells via a multitargeting mode of action, ie, through …

A panel of six new structurally related organometallic arene Ru (II) complexes of general
composition [(η6-benzene) Ru (L) Cl](1–3) and [(η6-p-cymene) Ru (L) Cl](4–6)(L …

Ruthenium (Ru) polypyridyl complexes have emerged as leading players among the
potential metal-based candidates for cancer treatment. However, the roles of cellular …