Clinical trials in REM sleep behavioural disorder: challenges and opportunities

A Videnovic, YES Ju, I Arnulf… - Journal of Neurology …, 2020 - jnnp.bmj.com
The rapid eye movement sleep behavioural disorder (RBD) population is an ideal study
population for testing disease-modifying treatments for synucleinopathies, since RBD …

Validation of an integrated software for the detection of rapid eye movement sleep behavior disorder

B Frauscher, D Gabelia, M Biermayr, A Stefani… - Sleep, 2014 - academic.oup.com
Abstract Study Objectives and Design: Rapid eye movement sleep without atonia (RWA) is
the polysomnographic hallmark of REM sleep behavior disorder (RBD). To partially …

REM sleep behavior disorder

CL Bassetti, P Bargiotas - … -Psychiatric Syndromes in Focus-Part I, 2018 - karger.com
Rapid eye movement sleep behavior disorder (RBD) is a brain disorder, characterized by
the dream enactment during rapid eye movement (REM) sleep due to a lack of physiologic …

Neurophysiological aspects of REM sleep behavior disorder (RBD): a narrative review

M Figorilli, G Lanza, P Congiu, R Lecca, E Casaglia… - Brain sciences, 2021 - mdpi.com
REM sleep without atonia (RSWA) is the polysomnographic (PSG) hallmark of rapid eye
movement (REM) sleep behavior disorder (RBD), a feature essential for the diagnosis of this …

Does idiopathic REM sleep behavior disorder (iRBD) really exist? What are the potential markers of neurodegeneration in iRBD?

L Ferini-Strambi - Sleep medicine, 2011 - Elsevier
REM sleep behavior disorder (RBD) may be idiopathic or associated with other neurologic
disorders. A strong association between RBD and α-synucleinopathies has recently been …

REM sleep behaviour disorder

L Ferini-Strambi, ML Fantini, M Zucconi… - Neurological …, 2005 - Springer
REM sleep behaviour disorder (RBD) is a parasomnia characterised by nocturnal complex
motor activity associated with dream mentation. RBD, which affects mainly older men, may …

Idiopathic REM sleep behavior disorder as a long-term predictor of neurodegenerative disorders

S Fulda, M Manconi - … Diseases: Integrative PPPM Approach as the …, 2013 - Springer
REM sleep behavior disorder (RBD) is a parasomnia characterized by dream-enacting
behavior and loss of muscle atonia during REM sleep. Idiopathic RBD occurs in the absence …

Objective rest–activity cycle analysis by actigraphy identifies isolated rapid eye movement sleep behavior disorder

M Filardi, A Stefani, E Holzknecht… - European Journal of …, 2020 - Wiley Online Library
Background and purpose Isolated rapid eye movement (REM) sleep behavior disorder
(iRBD) is characterized by abnormal behaviours during REM sleep. Several studies showed …

Rapid eye movement sleep without atonia constitutes increased risk for neurodegenerative disorders

HÖ Dede, G Benbir Senel… - Acta Neurologica …, 2019 - Wiley Online Library
Objectives REM (rapid eye movement) sleep without atonia (RSWA) is a polysomnographic
finding used in diagnosis of REM sleep behavior disorder (RBD). Clinical significance of …

Symptomatic REM sleep behaviour disorder

A Thomas, L Bonanni, M Onofrj - Neurological Sciences, 2007 - Springer
Rapid eye movement (REM) sleep behaviour disorder (RBD) precedes or accompanies
many neurodegenerative disorders. In synucleinopathies, including dementia with Lewy …